Pattaroni Céline
Department of Immunology, School of Translational Medicine, Monash University, Melbourne, VIC, Australia.
Immunol Cell Biol. 2025 Jan;103(1):6-8. doi: 10.1111/imcb.12837. Epub 2024 Nov 17.
In this article, we discuss a recently published study by Gopee et al., who have unveiled a surprising role for macrophages in human prenatal skin development, extending far beyond their traditional immune function. By constructing a comprehensive multi-omics single-cell atlas of human prenatal skin, they demonstrate that innate immune cells play a key role in hair follicle formation, scarless wound healing and neurovascular development.
在本文中，我们讨论了戈皮等人最近发表的一项研究，他们揭示了巨噬细胞在人类产前皮肤发育中出人意料的作用，其作用远远超出了它们传统的免疫功能。通过构建人类产前皮肤的全面多组学单细胞图谱，他们证明先天免疫细胞在毛囊形成、无瘢痕伤口愈合和神经血管发育中起关键作用。
