Department of Pediatrics, Université de Montréal, Montréal, Québec, Canada.
Department of Pediatrics, University of Washington, Seattle, Washington.
Pediatrics. 2024 Dec 1;154(6). doi: 10.1542/peds.2024-069298.
Nonmedical prescription drug use (NMPDU), the use of controlled prescription medications for purposes other than initially intended by the prescriber, is common among adolescents and young adults (AYAs). Prescription stimulants, sedatives, and opioid medications are the 3 main categories of controlled medications nonmedically used by AYAs. The intent of this clinical report is to provide an overview of the epidemiology, motives, sources, and risk factors of NMPDU among AYAs. This report also describes acute and long-term morbidity and mortality associated with NMPDU and discusses the importance of primary and secondary prevention to reduce the burden of NMPDU among AYAs. This report concludes with a series of recommendations on how pediatricians can address NMPDU with patients and their families.
非医疗目的处方药物使用（NMPDU），即患者出于非医疗目的使用医生开具的管制类处方药物，在青少年和年轻人（AYAs）中较为常见。处方兴奋剂、镇静剂和阿片类药物是非医疗目的使用的 3 类主要管制药物。本临床报告旨在概述 AYAs 中 NMPDU 的流行病学、动机、来源和风险因素。本报告还描述了与 NMPDU 相关的急性和长期发病率和死亡率，并讨论了初级和二级预防的重要性，以减轻 AYAs 中 NMPDU 的负担。最后，本报告就儿科医生如何与患者及其家属一起解决 NMPDU 问题提出了一系列建议。
