类鼻疽患者的隧道征：来自印度南部的病例系列
Tunnel sign in patients with melioidosis: a case series from South India.
作者信息
Gupta Nitin, Malla Sundeep, Kumar Tirlangi Praveen, Singh Sonali, Varma Muralidhar, Mukhopadhyay Chiranjay
机构信息
Department of Infectious Diseases, Kasturba Medical College, Manipal Academy of Higher Education, Manipal 576104, India.
Department of Radiodiagnosis, Amrita Institute of Medical Sciences, Faridabad 121002, India.
出版信息
Trans R Soc Trop Med Hyg. 2025 Jun 5;119(6):623-625. doi: 10.1093/trstmh/trae097.
INTRODUCTION
The tunnel sign (linear contrast enhancement along the corticospinal tract) can aid in the early diagnosis of neuromelioidosis, a potentially fatal condition requiring urgent diagnosis.
METHODOLOGY
We retrospectively analyzed the hospital data of all patients with culture-confirmed melioidosis between 2018 and 2023 in a tertiary care hospital in South India. MRI scans of patients with neuromelioidosis were reviewed for the presence of the tunnel sign.
RESULTS
Of the 177 patients with melioidosis, 21 had possible neurological involvement. Seven had confirmed neuromelioidosis. Of the six patients with neuromelioidosis, where an MRI scan was available, a tunnel sign was noted in four.
CONCLUSION
We report this study to create awareness amongst physicians to look for this sign in patients with suspected neuromelioidosis.
引言
隧道征（沿皮质脊髓束的线性对比增强）有助于神经类鼻疽病的早期诊断，这是一种需要紧急诊断的潜在致命疾病。
方法
我们回顾性分析了印度南部一家三级护理医院2018年至2023年间所有培养确诊类鼻疽病患者的医院数据。对神经类鼻疽病患者的MRI扫描进行了隧道征检查。
结果
在177例类鼻疽病患者中，21例可能有神经受累。7例确诊为神经类鼻疽病。在6例有MRI扫描的神经类鼻疽病患者中，4例发现有隧道征。
结论
我们报告这项研究，以提高医生对疑似神经类鼻疽病患者中寻找此征的认识。
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