• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

乔治·戈莫里对糖尿病研究的贡献及……的起源

George Gomori's Contributions to Diabetes Research and the Origins of the .

作者信息

Baskin Denis G

机构信息

Division of Metabolism, Endocrinology, and Nutrition, Department of Medicine, University of Washington, Seattle, Washington (DGB).

出版信息

J Histochem Cytochem. 2024 Nov-Dec;72(11-12):729-731. doi: 10.1369/00221554241300370. Epub 2024 Nov 18.

DOI:10.1369/00221554241300370
PMID:39552432
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11572951/
Abstract

Over a period of almost 30 years, Gomori was one of the most prolific and productive investigators in the emerging field of enzyme histochemistry and was recognized by his peers as a pioneer in developing methods for the histochemical demonstration of hydrolytic enzyme activity, most notably phosphatases, esterases, and lipases. Gomori also made important contributions to diabetes research by developing histological techniques that reliably stained the insulin-secreting B cell of the pancreatic islets of Langerhans. Gomori's aldehyde fuchsin staining method was standard for pathological and physiological studies on islet B cells in relation to diabetes and obesity until insulin antibodies became widely available for immunohistochemical identification of B cells. Gomori was a founding member of The Histochemical Society in 1950. When the HCS established the in 1953, Gomori served as one of the first Associate Editors. He also served as President of The Histochemical Society.

摘要

在近30年的时间里,戈莫里是新兴的酶组织化学领域最多产、最有成果的研究者之一,被同行公认为是开发水解酶活性组织化学显示方法的先驱,最著名的是磷酸酶、酯酶和脂肪酶。戈莫里还通过开发能可靠地对胰岛中分泌胰岛素的β细胞进行染色的组织学技术,为糖尿病研究做出了重要贡献。在胰岛素抗体广泛用于β细胞的免疫组织化学鉴定之前,戈莫里的醛复红染色法一直是胰岛β细胞与糖尿病和肥胖相关的病理和生理研究的标准方法。戈莫里是1950年组织化学学会的创始成员之一。1953年组织化学学会设立该杂志时,戈莫里担任首批副主编之一。他还担任过组织化学学会会长。

相似文献

1
George Gomori's Contributions to Diabetes Research and the Origins of the .乔治·戈莫里对糖尿病研究的贡献及……的起源
J Histochem Cytochem. 2024 Nov-Dec;72(11-12):729-731. doi: 10.1369/00221554241300370. Epub 2024 Nov 18.
2
A Historical Perspective on the Identification of Cell Types in Pancreatic Islets of Langerhans by Staining and Histochemical Techniques.通过染色和组织化学技术鉴定胰岛细胞类型的历史视角
J Histochem Cytochem. 2015 Aug;63(8):543-58. doi: 10.1369/0022155415589119.
3
Nuclear histochemistry: Its history in fifty volumes.《核组织化学:五十卷的历史》
Eur J Histochem. 2006 Jan-Mar;50(1):79-81.
4
From the History of the Croatian Dermatovenereological Society - The Croatian Medical Association and an Overview of Important Information Regarding the Journal Acta Dermatovenerologica Croatica.克罗地亚皮肤性病学会史——克罗地亚医学协会及《克罗地亚皮肤性病学学报》重要信息概述
Acta Dermatovenerol Croat. 2018 Dec;26(4):344-348.
5
Celebration of the 50th anniversary of publication of Histochemistry and Cell Biology.《组织化学与细胞生物学》出版50周年庆典。
Histochem Cell Biol. 2008 Jan;129(1):1-3. doi: 10.1007/s00418-007-0353-z.
6
[Gomori reactions in orthology and pathology].[同源性与病理学中的戈莫里反应]
Zentralbl Allg Pathol. 1990;136(3):211-7.
7
Histochemistry through the years, browsing a long-established journal: novelties in traditional subjects.多年来的组织化学,浏览一本历史悠久的期刊:传统主题的新进展。
Eur J Histochem. 2010 Dec 16;54(4):e51. doi: 10.4081/ejh.2010.e51.
8
Diagnostic histochemistry: A historical perspective.诊断组织化学:历史视角
Semin Diagn Pathol. 2018 Nov;35(6):354-359. doi: 10.1053/j.semdp.2018.10.007. Epub 2018 Oct 16.
9
The impact of histochemistry--a historical perspective.组织化学的影响——历史视角
Acta Histochem. 2000 Feb;102(1):5-14. doi: 10.1078/0065-1281-00542.
10
Histochemistry: historical development and current use in pathology.组织化学:病理学中的历史发展与当前应用
Biotech Histochem. 2014 Feb;89(2):81-90. doi: 10.3109/10520295.2013.822559. Epub 2013 Aug 19.

本文引用的文献

1
A Historical Perspective on the Identification of Cell Types in Pancreatic Islets of Langerhans by Staining and Histochemical Techniques.通过染色和组织化学技术鉴定胰岛细胞类型的历史视角
J Histochem Cytochem. 2015 Aug;63(8):543-58. doi: 10.1369/0022155415589119.
2
A differential stain for cell types in the pancreatic islets.一种用于胰岛中细胞类型的鉴别染色法。
Am J Pathol. 1939 Jul;15(4):497-499.2. doi: 10.1093/ajcp/10.ts4_1.28.
3
A rapid one-step trichrome stain.一种快速的一步三色染色法。
Am J Clin Pathol. 1950 Jul;20(7):661-4. doi: 10.1093/ajcp/20.7_ts.661.
4
Evidence for the D-cell of the pancreas secreting somatostatin.胰腺D细胞分泌生长抑素的证据。
Horm Metab Res. 1975 Sep;7(5):400-2. doi: 10.1055/s-0028-1093736.