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通过生活方式改变治愈视网膜脂血症

Resolution of Lipemia Retinalis With Lifestyle Modification.

作者信息

Prairie Michael L, Rubino Shaina M, Tang Peter H

机构信息

University of Minnesota Medical School, Minneapolis, MN, USA.

Retina Associates, PA, Winchester, VA, USA.

出版信息

J Vitreoretin Dis. 2024 Aug 31;8(6):728-730. doi: 10.1177/24741264241275285. eCollection 2024 Nov-Dec.

DOI:10.1177/24741264241275285
PMID:39554632
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11561956/
Abstract

To describe a case of lipemia retinalis, a rare ocular manifestation of hypertriglyceridemia that is characterized by a creamy-white to salmon-colored appearance to the fundus. A 55-year-old man was referred for an evaluation for diabetic retinopathy and was subsequently found to have marked lipemia retinalis. The patient's triglyceride levels were 3141 mg/dL; therefore, treatment was initiated with high-intensity statin therapy and lifestyle modifications. At the 3-month follow-up, the patient had significantly reduced triglyceride levels (689 mg/dL) and full resolution of lipemia retinalis. Lipemia retinalis may be an initial finding of a severe systemic problem and a harbinger for more severe, and potentially fatal, consequences. Thus, a complete systemic assessment is warranted for any patient with signs of lipemia retinalis.

摘要

描述一例视网膜脂血症,这是一种罕见的高甘油三酯血症眼部表现,其特征为眼底呈乳白至鲑鱼色外观。一名55岁男性因糖尿病视网膜病变评估前来就诊,随后被发现患有明显的视网膜脂血症。患者甘油三酯水平为3141mg/dL;因此,开始采用高强度他汀类药物治疗并进行生活方式调整。在3个月的随访中,患者甘油三酯水平显著降低(689mg/dL),视网膜脂血症完全消退。视网膜脂血症可能是严重全身问题的初始表现,也是更严重且可能致命后果的先兆。因此,对于任何有视网膜脂血症体征的患者,都有必要进行全面的全身评估。

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本文引用的文献

1
Alterations in ocular microcirculation and oxygen metabolism in patients with lipemia retinalis.脂血症性视网膜病变患者眼微循环和氧代谢的改变。
BMC Ophthalmol. 2022 Jul 6;22(1):295. doi: 10.1186/s12886-022-02515-7.
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Lipemia retinalis preceding acute pancreatitis.急性胰腺炎之前出现的视网膜脂血症。
Optometry. 2011 Aug;82(8):475-80. doi: 10.1016/j.optm.2011.01.011. Epub 2011 May 12.
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Novel LPL mutations associated with lipoprotein lipase deficiency: two case reports and a literature review.与脂蛋白脂肪酶缺乏症相关的新型脂蛋白脂肪酶突变:两例病例报告及文献综述
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Hypertriglyceridemia: its etiology, effects and treatment.高甘油三酯血症:其病因、影响及治疗
CMAJ. 2007 Apr 10;176(8):1113-20. doi: 10.1503/cmaj.060963.
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Electrophysiological changes in lipaemia retinalis.视网膜脂血症的电生理变化。
Am J Ophthalmol. 2005 Jun;139(6):1142-5. doi: 10.1016/j.ajo.2004.12.021.
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Lipemia retinalis associated with branch retinal vein occlusion.视网膜脂血症伴视网膜分支静脉阻塞。
Am J Ophthalmol. 2003 Apr;135(4):539-42. doi: 10.1016/s0002-9394(02)02076-7.
7
Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III).国家胆固醇教育计划(NCEP)成人高血胆固醇检测、评估与治疗专家小组第三次报告(成人治疗小组第三次报告)执行摘要
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