Mansoor Afsheen, Mansoor Emaan, Amir Nehal, Hussain Khadim
Afsheen Mansoor, PhD (Medical Microbiology, Dental Materials, Nanotechnology), Associate Professor, Quaid-i-Azam University, Islamabad, Pakistan. Department of Dental Material Sciences, School of Dentistry, Shaheed Zulfiqar Ali Bhutto Medical University, Islamabad, Pakistan.
Emaan Mansoor, Islamic International Dental College, Riphah International University, Islamabad, Pakistan.
Pak J Med Sci. 2024 Nov;40(10):2331-2335. doi: 10.12669/pjms.40.10.9826.
To evaluate the effectiveness of Azadirachta indica based Herbal mouthwash to treat tooth sensitivity in patients.
This single-blinded clinical trial was performed at School of dentistry, Shaheed Zulfiqar Ali Bhutto Medial University, Islamabad from 1st February, 2023 to 30th April, 2023. In this interventional study incorporated 120 participants with clinically visible signs of erosion, abrasion or recession. Visual Analog Scoring (VAS) Tool was used to investigate tooth sensitivity in these patients. Values of VAS for tooth sensitivity was calculated by exposing teeth of these patients to cold air blasting with triple syringe attached to dental unit at psi-30.0 pressure between 23±30ºC for duration of one second without using Azadirachta indica based Herbal mouthwash. Later on, these patients were provided with this Herbal mouthwash and its usage was recommended twice a day for one month. After One month, tooth sensitivity of patients was determined by VAS again. Data was analyzed by Paired T-test at 95% confidence and significance < 0.05.
VAS mean value for tooth sensitivity of patients before using based Herbal mouthwash was higher and found to be 55.43% ± 12.04 whereas its mean value after using Herbal mouthwash for one month reduced to 35.38% ± 11.62 which was statistically significant ( value=0.001). Reduction in tooth sensitivity of patients was almost 20.05% just after one month.
based Herbal mouthwash was potent enough to reduce the tooth sensitivity in patients after one month of its usage.
评估印楝基草本漱口水治疗患者牙齿敏感的有效性。
这项单盲临床试验于2023年2月1日至2023年4月30日在伊斯兰堡沙希德·祖尔菲卡尔·阿里·布托医科大学牙科学院进行。在这项干预性研究中,纳入了120名有临床可见的侵蚀、磨损或牙龈退缩迹象的参与者。使用视觉模拟评分(VAS)工具调查这些患者的牙齿敏感情况。通过将这些患者的牙齿暴露于连接到牙科设备的三联注射器在23±30ºC、30.0磅力/平方英寸压力下以每秒1秒的持续时间进行冷空气喷射,在不使用印楝基草本漱口水的情况下计算牙齿敏感的VAS值。之后,为这些患者提供这种草本漱口水,并建议每天使用两次,持续一个月。一个月后,再次通过VAS确定患者的牙齿敏感情况。数据采用配对t检验进行分析,置信度为95%,显著性<0.05。
患者在使用印楝基草本漱口水前牙齿敏感的VAS平均值较高,为55.43%±12.04,而使用草本漱口水一个月后的平均值降至35.38%±11.62,具有统计学意义(p值=0.001)。仅一个月后,患者牙齿敏感的降低率几乎达到20.05%。
印楝基草本漱口水在使用一个月后足以有效降低患者的牙齿敏感。