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米氮平：用于治疗接受姑息治疗的转移性肉瘤患者的慢性难治性恶心和呕吐的一种抗抑郁药：病例报告

Mirtazapine: An Antidepressant for Treating Chronic, Refractory Nausea and Vomiting in a Patient With Metastatic Sarcoma Receiving Palliative Care: A Case Report.

作者信息

Ziaei Seyedeh Golnaz, Tahmasebi Mamak

机构信息

Division of Palliative Medicine, Radio Oncology Department Tehran University of Medical Sciences Tehran Iran.

Cancer Research Center Cancer Institute, Imam Khomeini Hospital, Tehran University of Medical Sciences Tehran Iran.

出版信息

Clin Case Rep. 2024 Nov 14;12(11):e9570. doi: 10.1002/ccr3.9570. eCollection 2024 Nov.

DOI:10.1002/ccr3.9570
PMID:39555208
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11564124/
Abstract

Managing chronic, refractory nausea and vomiting in advanced cancer patients is challenging, especially when unrelated to cancer treatment. Mirtazapine, a tetracyclic antidepressant, effectively alleviates these symptoms, improving quality of life. It offers a promising palliative care alternative, addressing multiple symptoms and reducing polypharmacy, thereby enhancing patient satisfaction.

摘要

管理晚期癌症患者的慢性难治性恶心和呕吐具有挑战性，尤其是当这些症状与癌症治疗无关时。米氮平，一种四环类抗抑郁药，能有效缓解这些症状，提高生活质量。它提供了一种有前景的姑息治疗选择，可解决多种症状并减少联合用药，从而提高患者满意度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74c1/11564124/397426e5ca3a/CCR3-12-e9570-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74c1/11564124/397426e5ca3a/CCR3-12-e9570-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74c1/11564124/397426e5ca3a/CCR3-12-e9570-g001.jpg

相似文献

1
Mirtazapine: An Antidepressant for Treating Chronic, Refractory Nausea and Vomiting in a Patient With Metastatic Sarcoma Receiving Palliative Care: A Case Report.米氮平：用于治疗接受姑息治疗的转移性肉瘤患者的慢性难治性恶心和呕吐的一种抗抑郁药：病例报告
Clin Case Rep. 2024 Nov 14;12(11):e9570. doi: 10.1002/ccr3.9570. eCollection 2024 Nov.
2
Novel therapies for nausea and vomiting in advanced illness and supportive cancer care.晚期疾病及癌症支持治疗中恶心和呕吐的新型疗法。
Palliat Care Soc Pract. 2024 Jun 6;18:26323524241257701. doi: 10.1177/26323524241257701. eCollection 2024.
3
Other Antidepressants.其他抗抑郁药。
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[Treatment of nausea and vomiting with 5HT3 receptor antagonists, steroids, antihistamines, anticholinergics, somatostatinantagonists, benzodiazepines and cannabinoids in palliative care patients : a systematic review].[5-羟色胺3受体拮抗剂、类固醇、抗组胺药、抗胆碱能药、生长抑素拮抗剂、苯二氮卓类药物和大麻素类药物用于姑息治疗患者恶心呕吐的治疗：一项系统评价]
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Mirtazapine for symptom control in refractory gastroparesis.米氮平用于难治性胃轻瘫的症状控制。
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本文引用的文献

1
Novel therapies for nausea and vomiting in advanced illness and supportive cancer care.晚期疾病及癌症支持治疗中恶心和呕吐的新型疗法。
Palliat Care Soc Pract. 2024 Jun 6;18:26323524241257701. doi: 10.1177/26323524241257701. eCollection 2024.
2
Mirtazapine: A One-Stop Strategy for Treatment of Opioid Withdrawal Symptoms.米氮平：治疗阿片类药物戒断症状的一站式策略。
Cureus. 2023 Aug 20;15(8):e43821. doi: 10.7759/cureus.43821. eCollection 2023 Aug.
3
The Management of Nausea and Vomiting Not Related to Anticancer Therapy in Patients with Cancer.
癌症患者非抗肿瘤治疗相关恶心呕吐的管理。
Curr Treat Options Oncol. 2021 Jan 14;22(2):17. doi: 10.1007/s11864-020-00813-0.
4
Nausea and Vomiting Not Related to Cancer Therapy: Intractable Problem or Clinical Challenge?与癌症治疗无关的恶心和呕吐：棘手问题还是临床挑战？
J Adv Pract Oncol. 2020 Jul;11(5):476-488. doi: 10.6004/jadpro.2020.11.5.4. Epub 2020 Jul 1.
5
Antiemetics: ASCO Guideline Update.止吐药：ASCO 指南更新。
J Clin Oncol. 2020 Aug 20;38(24):2782-2797. doi: 10.1200/JCO.20.01296. Epub 2020 Jul 13.
6
Olanzapine for the Treatment of Advanced Cancer-Related Chronic Nausea and/or Vomiting: A Randomized Pilot Trial.奥氮平治疗晚期癌症相关慢性恶心和/或呕吐的随机试验。
JAMA Oncol. 2020 Jun 1;6(6):895-899. doi: 10.1001/jamaoncol.2020.1052.
7
Nausea and Vomiting in Advanced Cancer.晚期癌症患者的恶心和呕吐。
Curr Treat Options Oncol. 2020 Feb 5;21(2):14. doi: 10.1007/s11864-020-0704-8.
8
Palliative Care and the Management of Common Distressing Symptoms in Advanced Cancer: Pain, Breathlessness, Nausea and Vomiting, and Fatigue.姑息治疗与晚期癌症常见痛苦症状的管理：疼痛、呼吸困难、恶心和呕吐以及疲劳。
J Clin Oncol. 2020 Mar 20;38(9):905-914. doi: 10.1200/JCO.19.00470. Epub 2020 Feb 5.
9
Mirtazapine's effect on the QT interval in medically hospitalized patients.米氮平对内科住院患者QT间期的影响。
Ment Health Clin. 2020 Jan 9;10(1):30-33. doi: 10.9740/mhc.2020.01.030. eCollection 2020 Jan.
10
What is the evidence for mirtazapine in treating cancer-related symptomatology? A systematic review.米氮平治疗癌症相关症状的证据有哪些？系统评价。
Support Care Cancer. 2020 Apr;28(4):1597-1606. doi: 10.1007/s00520-019-05229-7. Epub 2019 Dec 19.