Ghosh Mainak, Hegde Adarsh Ishwar, Ganesan Aparna, Badgurjar Saurabh
Department of Oral Oncology, Kidwai Memorial Institute of Oncology, Bengaluru, India.
Kasturba Medical College, Manipal, India.
Indian J Surg Oncol. 2024 Dec;15(4):796-801. doi: 10.1007/s13193-024-01998-8. Epub 2024 Jun 27.
Depth of invasion (DOI) is an established independent prognostic factor in oral squamous cell carcinoma (OSCC) and also predicts cervical nodal metastasis. Preoperative determination of DOI based on imaging can aid in decision-making regarding neck dissection or determining the prognosis of the disease. This study aimed to correlate the DOI measured on contrast enhanced computed tomography (rDOI) with the pathologically measured DOI (pDOI). Retrospective data of patients with OSCC of the gingivobuccal complex from January 2023 to July 2023 was collected. Two radiologists independently measured the DOI on axial and coronal planes of CECT. The correlation between rDOI and pDOI was determined. Stepwise multiple linear regression analysis was performed to predict the pDOI using rDOI. ROC curve analysis was performed for the rDOI as measured on both axial and coronal sections in predicting the nodal metastasis. A total of 59 patients were included in the study. The mean rDOI was 11.06 mm on axial section and 10.9 mm on coronal section, and pDOI was 9.7 mm. Spearman's correlation coefficient between pDOI and rDOI measured on axial (rho = 0.61; value = 0.001) and coronal (rho = 0.62; value = 0.001) sections implied strong correlation which was statistically significant. The present study attempted to establish the correlation and accuracy of CECT-determined rDOI in axial and coronal planes in gingivobuccal complex tumours. Multicentric studies with a larger sample size are mandated to augment the results obtained in this study.
The online version contains supplementary material available at 10.1007/s13193-024-01998-8.
浸润深度（DOI）是口腔鳞状细胞癌（OSCC）中已确定的独立预后因素，并且还可预测颈部淋巴结转移。基于影像学的术前DOI测定有助于关于颈部清扫术的决策制定或确定疾病的预后。本研究旨在将对比增强计算机断层扫描测量的DOI（rDOI）与病理测量的DOI（pDOI）进行相关性分析。收集了2023年1月至2023年7月牙龈颊复合体OSCC患者的回顾性数据。两名放射科医生独立在CECT的轴位和冠状位平面上测量DOI。确定rDOI与pDOI之间的相关性。进行逐步多元线性回归分析以使用rDOI预测pDOI。对轴位和冠状位测量的rDOI进行ROC曲线分析以预测淋巴结转移。本研究共纳入59例患者。轴位平均rDOI为11.06mm，冠状位为10.9mm，pDOI为9.7mm。在轴位（rho = 0.61；p值 = 0.001）和冠状位（rho = 0.62；p值 = 0.001）测量的pDOI与rDOI之间的Spearman相关系数表明存在强相关性且具有统计学意义。本研究试图确定牙龈颊复合体肿瘤在轴位和冠状位平面上CECT测定的rDOI的相关性和准确性。需要进行更大样本量的多中心研究以增强本研究获得的结果。
在线版本包含可在10.1007/s13193-024-01998-8获取的补充材料。
