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原位肾自体移植：化疗后腹膜后淋巴结清扫治疗生殖细胞肿瘤的一项进展。

Orthotopic renal autotransplantation: A step forward during postchemotherapy retroperitoneal lymph node dissection for germ cell tumor.

作者信息

Mor Akash, Gujela Ajit, Patel Sachin, Kumar Vineet, Prakash Gagan

机构信息

Division of Uro-Oncology, Department of Surgical Oncology, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, India.

Department of Plastic and Reconstructive Surgery, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, India.

出版信息

Indian J Urol. 2024 Oct-Dec;40(4):273-275. doi: 10.4103/iju.iju_48_24. Epub 2024 Oct 1.

DOI:10.4103/iju.iju_48_24
PMID:39555432
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11567579/
Abstract

We present the first and a rare case of orthotopic renal auto-transplantation in the management of postchemotherapy residual retroperitoneal mass encasing the left renal vessels but sparing the parenchyma in a 24-year-old patient with Stage IIIC nonseminomatous germ cell tumor after 4 cycles of chemotherapy. Immediate postoperative and 6 months' follow-up renograms confirmed the maintained glomerular filtration rate of the transplanted kidney with no residual disease. This case report shows the feasibility of renal autotransplantation in carefully selected patients as they are young and have long-term survival.

摘要

我们报告了首例且罕见的原位肾自体移植病例，该病例是一名24岁的IIIC期非精原细胞瘤性生殖细胞肿瘤患者，在接受4个周期化疗后，采用原位肾自体移植来处理化疗后残留的包裹左肾血管但未累及肾实质的腹膜后肿块。术后即刻及6个月随访的肾图检查证实移植肾的肾小球滤过率得以维持，且无残留疾病。本病例报告显示，对于经过精心挑选的年轻且有望长期存活的患者，肾自体移植是可行的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e051/11567579/58e5940b175c/IJU-40-273-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e051/11567579/d5af25fe5b04/IJU-40-273-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e051/11567579/58e5940b175c/IJU-40-273-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e051/11567579/d5af25fe5b04/IJU-40-273-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e051/11567579/58e5940b175c/IJU-40-273-g002.jpg

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本文引用的文献

1
Kidney Autotransplantation in the Management of Residual Retroperitoneal Mass in a Germ Cell Tumor.肾自体移植在生殖细胞瘤残余腹膜后肿块治疗中的应用。
Transplant Proc. 2022 Jul-Aug;54(6):1583-1588. doi: 10.1016/j.transproceed.2022.03.056. Epub 2022 Jul 28.
2
Outcomes of Postchemotherapy Retroperitoneal Lymph Node Dissection from a High-volume UK Centre Compared with a National Data Set.英国一家大型中心与全国数据集相比，化疗后腹膜后淋巴结清扫术的结果
Eur Urol Open Sci. 2021 Sep 30;33:83-88. doi: 10.1016/j.euros.2021.09.005. eCollection 2021 Nov.
3
Renal autotransplantation in postchemotherapy retroperitoneal lymph node dissection: a case report.
化疗后腹膜后淋巴结清扫术中的肾自体移植：一例报告
Urol J. 2014 Mar 4;11(1):1362-5.
4
Complications of post-chemotherapy retroperitoneal lymph node dissection for testis cancer.睾丸癌化疗后腹膜后淋巴结清扫术的并发症
J Urol. 2004 May;171(5):1839-41. doi: 10.1097/01.ju.0000120141.89737.90.
5
[Retroperitoneal lymph node dissection for testicular tumor with renal autotransplantation: a case report].[睾丸肿瘤行腹膜后淋巴结清扫术并自体肾移植：1例报告]
Hinyokika Kiyo. 1990 Mar;36(3):359-62.