DeSisto Nicole G, Longino Elizabeth S, Ortiz Alexandra S, Chowdhury Naweed I, Patel Priyesh N, Stephan Scott J, Yang Shiayin F
Department of Otolaryngology-Head and Neck Surgery, Division of Facial Plastic and Reconstructive Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Otolaryngol Head Neck Surg. 2025 Feb;172(2):436-443. doi: 10.1002/ohn.1001. Epub 2024 Nov 18.
Synkinesis is estimated to impact 10% to 50% of those with facial palsy. We aim to identify the incidence and factors associated with anxiety and depression in the facial synkinesis population.
Prospective cohort study.
Patients aged 18 and older with a diagnosis of facial synkinesis at a tertiary medical center were eligible for inclusion.
Demographic variables were collected, and the following surveys were distributed: Synkinesis Assessment Questionnaire, Facial Clinimetric Evaluation Scale, Facial Disability Index, Center for Epidemiological Studies Depression Scale, and Fear of Negative Appearance Evaluation Scale. Patient videos were graded for physician perceived severity using the Electronic Facial Paralysis Assessment and Sunnybrook scale. Analysis of the overall incidence of anxiety and depression symptoms as well as the impact of demographic factors was performed using Pearson product moment correlation and regression modeling.
One-hundred patients met inclusion criteria. Over 25% of patients met criteria for possible or probable depression and the most common appearance-related anxiety score was 30, indicating severe anxiety. Female gender, younger age, and previous history of anxiety and depression were associated with increased depression and anxiety scores at baseline with shorter duration of synkinesis also trending toward higher scores. Worse patient reported severity was also associated with increased depression and appearance-related anxiety scores.
The overall prevalence of depression and appearance-related anxiety is relatively high in patients with facial synkinesis.
据估计，联动运动影响10%至50%的面瘫患者。我们旨在确定面瘫联动运动人群中焦虑和抑郁的发生率及相关因素。
前瞻性队列研究。
在一家三级医疗中心，年龄18岁及以上且诊断为面瘫联动运动的患者符合纳入标准。
收集人口统计学变量，并发放以下调查问卷：联动运动评估问卷、面部临床测量评估量表、面部残疾指数、流行病学研究中心抑郁量表和负面外观恐惧评估量表。使用电子面瘫评估和桑尼布鲁克量表对患者视频进行分级，以评估医生感知的严重程度。使用皮尔逊积差相关和回归模型分析焦虑和抑郁症状的总体发生率以及人口统计学因素的影响。
100名患者符合纳入标准。超过25%的患者符合可能或很可能患有抑郁症的标准，最常见的与外观相关的焦虑评分为30分，表明存在严重焦虑。女性、较年轻的年龄以及既往焦虑和抑郁病史与基线时抑郁和焦虑评分增加相关，联动运动持续时间较短也倾向于较高的评分。患者报告的病情越严重，抑郁和与外观相关的焦虑评分也越高。
面瘫联动运动患者中抑郁和与外观相关的焦虑的总体患病率相对较高。
