Baker L R, Cattell W R, Fry I K, Mallinson W J
Q J Med. 1979 Oct;48(192):603-12.
Five patients who presented with acute renal failure in association with urinary tract infection are reported. Renal function improved rapidly on antibacterial therapy and no alternative cause for acute renal failure could be identified. None had previously been known to have renal disease but three of the five had taken considerable amounts of analgesics. The unusual severity of renal functional impairment resulting from urinary tract infection in these patients is unexplained but may relate to previous analgesic abuse and/or delay in treatment. Since acute non-obstructive pyelonephritis may result in severe reversible renal failure, this diagnosis must be considered in patients presenting with acute uraemia.
报告了5例伴有尿路感染的急性肾衰竭患者。抗菌治疗后肾功能迅速改善，未发现急性肾衰竭的其他病因。此前均不知他们患有肾脏疾病，但5例中有3例服用了大量镇痛药。这些患者因尿路感染导致的肾功能损害异常严重，原因不明，但可能与既往滥用镇痛药和/或治疗延误有关。由于急性非梗阻性肾盂肾炎可能导致严重的可逆性肾衰竭，对于出现急性尿毒症的患者必须考虑这一诊断。
