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Best in Class: IgG as a Treatable Trait for Exacerbation Prevention in Chronic Obstructive Pulmonary Disease.

作者信息

Wang Carolyn J, Sin Don D

机构信息

Centre for Heart Lung Innovation St. Paul's Hospital Vancouver, British Columbia, Canada.

Department of Medicine University of British Columbia Vancouver, British Columbia, Canada.

出版信息

Am J Respir Crit Care Med. 2025 Feb;211(2):144-146. doi: 10.1164/rccm.202409-1681ED.

DOI:10.1164/rccm.202409-1681ED
PMID:39556414
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11812549/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a551/11812549/c8fb81305900/rccm.202409-1681EDf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a551/11812549/c8fb81305900/rccm.202409-1681EDf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a551/11812549/c8fb81305900/rccm.202409-1681EDf1.jpg

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本文引用的文献

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Serum Immunoglobulin G Levels Are Associated with Risk for Exacerbations: An Analysis of SPIROMICS.血清免疫球蛋白G水平与急性加重风险相关：SPIROMICS分析
Am J Respir Crit Care Med. 2025 Feb;211(2):215-221. doi: 10.1164/rccm.202311-2184OC.
2
Dupilumab for COPD with Blood Eosinophil Evidence of Type 2 Inflammation.针对伴有血液嗜酸性粒细胞证据的 2 型炎症 COPD 患者的度普利尤单抗。
N Engl J Med. 2024 Jun 27;390(24):2274-2283. doi: 10.1056/NEJMoa2401304. Epub 2024 May 20.
3
Effectiveness of immunoglobulin replacement therapy in preventing infections in patients with chronic obstructive pulmonary disease: a systematic review.
免疫球蛋白替代疗法预防慢性阻塞性肺疾病患者感染的有效性：一项系统评价
Allergy Asthma Clin Immunol. 2024 Apr 10;20(1):30. doi: 10.1186/s13223-024-00886-8.
4
The impact of IgG subclass deficiency on the risk of mortality in hospitalized patients with COPD.IgG 亚类缺陷对住院 COPD 患者死亡风险的影响。
Respir Res. 2022 May 31;23(1):141. doi: 10.1186/s12931-022-02052-3.
5
Serological analysis reveals an imbalanced IgG subclass composition associated with COVID-19 disease severity.血清学分析显示，与 COVID-19 疾病严重程度相关的 IgG 亚类组成失衡。
Cell Rep Med. 2021 Jul 20;2(7):100329. doi: 10.1016/j.xcrm.2021.100329. Epub 2021 Jun 15.
6
High-resolution computed tomography findings in humoral primary immunodeficiencies and correlation with pulmonary function tests.体液原发性免疫缺陷的高分辨率计算机断层扫描结果及其与肺功能测试的相关性。
World J Radiol. 2018 Nov 28;10(11):172-183. doi: 10.4329/wjr.v10.i11.172.
7
Serum IgG subclass levels and risk of exacerbations and hospitalizations in patients with COPD.血清 IgG 亚类水平与 COPD 患者加重和住院风险的关系。
Respir Res. 2018 Feb 14;19(1):30. doi: 10.1186/s12931-018-0733-z.
8
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report. GOLD Executive Summary.慢性阻塞性肺疾病全球策略：诊断、管理与预防 2017 年报告。GOLD 执行摘要。
Am J Respir Crit Care Med. 2017 Mar 1;195(5):557-582. doi: 10.1164/rccm.201701-0218PP.
9
Azithromycin for prevention of exacerbations of COPD.阿奇霉素预防 COPD 加重。
N Engl J Med. 2011 Aug 25;365(8):689-98. doi: 10.1056/NEJMoa1104623.
10
Antigen-Specific IgG ameliorates allergic airway inflammation via Fcγ receptor IIB on dendritic cells.抗原特异性 IgG 通过树突状细胞上的 Fcγ 受体 IIB 改善过敏性气道炎症。
Respir Res. 2011 Apr 10;12(1):42. doi: 10.1186/1465-9921-12-42.