Liang Shiwei, Ott Brian R, Tjia Jennifer, Lapane Kate L, Rataj Alison C, Alcusky Matthew
Department of Population and Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, USA.
Department of Neurology, Brown University Warren Alpert Medical School, Providence, RI, USA.
J Am Med Dir Assoc. 2025 Jan;26(1):105358. doi: 10.1016/j.jamda.2024.105358. Epub 2024 Nov 15.
Nursing home (NH) administrator perceptions regarding the utility of Alzheimer's disease (AD) disease-modifying medications in NHs are important because many short and long-stay residents have mild AD. This study examined the interest of directors of nursing (DoNs) in using new AD disease-modifying treatments, changes in attitudes based on differences in costs to the NH, and characteristics (DoN and NH) associated with such changes.
This is a cross-sectional study.
This study is based on a 2022 nationally representative survey of 340 NH DoNs, which was drawn from a stratified random sample of US NHs with ≥30 beds and with a 26.6% response rate.
We conducted a descriptive analysis to assess the awareness of new AD disease-modifying treatments and the support for their use. We applied logistic regression models to explore the associations between the interest of the DoN in using these new AD treatments and various characteristics.
Most (86%) DoNs stated that they would at least sometimes support the usage of a new disease-modifying medication if there were no NH costs. This percentage was lower if the NH costs per resident were $2000 per year (51.3%) and $20,000 per year (14%). NHs with moderate shares of dual-eligible residents were more sensitive to cost.
Our findings indicated that the interest of DoNs in using disease-modifying treatments for dementia varies widely according to the cost to the NHs. The uptake of new AD medications in the NH setting should be monitored, and targeted efforts may be needed to mitigate inequities in access for less-resourced NHs.
养老院管理人员对阿尔茨海默病(AD)疾病修饰药物在养老院效用的看法很重要,因为许多短期和长期居住的居民患有轻度AD。本研究调查了护理主任(DoN)对使用新型AD疾病修饰疗法的兴趣、基于养老院成本差异的态度变化以及与此类变化相关的特征(护理主任和养老院)。
这是一项横断面研究。
本研究基于2022年对340名养老院护理主任进行的全国代表性调查,这些护理主任来自美国拥有≥30张床位的养老院的分层随机样本,回复率为26.6%。
我们进行了描述性分析,以评估对新型AD疾病修饰疗法的认识以及对其使用的支持。我们应用逻辑回归模型来探索护理主任对使用这些新型AD疗法的兴趣与各种特征之间的关联。
大多数(86%)护理主任表示,如果养老院无需承担成本,他们至少有时会支持使用新型疾病修饰药物。如果每位居民每年的养老院成本为2000美元(51.3%)和20000美元(14%),这一比例会更低。具有适度双重资格居民比例的养老院对成本更为敏感。
我们的研究结果表明,护理主任对使用痴呆症疾病修饰疗法的兴趣因养老院的成本而异。应监测养老院环境中新型AD药物的使用情况,可能需要有针对性的努力来减少资源较少的养老院在获取药物方面的不平等现象。