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[创伤的黄金处理方法。优化院前创伤护理需要哪些血液制品?]

[The golden approach to trauma. Which blood products are needed for optimization of prehospital trauma care?].

作者信息

Bamberg Maximilian Lothar, Grasshoff Christian, Gerstner Jessica, Boos Matthias Fabian, Bentele Michael, Viergutz Tim, Fontana Johann, Rosenberger Peter, Wunderlich Robert

机构信息

Abteilung für Anästhesiologie und Intensivmedizin, BG Unfallklinik Tübingen, Tübingen, Deutschland.

Universitätsklinik für Anästhesiologie und Intensivmedizin, Universitätsklinikum Tübingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Deutschland.

出版信息

Anaesthesiologie. 2024 Dec;73(12):819-828. doi: 10.1007/s00101-024-01482-6. Epub 2024 Nov 18.

Abstract

BACKGROUND

The golden hour of trauma denotes the critical first hour after severe injury where timely medical response is crucial, although scientific support for this time frame is inconsistent. This study emphasizes optimizing trauma care by tailoring treatment to the specific injury rather than focusing solely on the speed of treatment. The aim is to document the need for improvement in prehospital trauma care, particularly by the use of blood and coagulation products.

METHODS

After a pilot study, a purpose-designed online questionnaire targeted at German physicians and rescue service personnel was utilized to collect their views on general trauma care and specifically on the use of blood and coagulation products in prehospital settings. It also assessed the appropriateness of nine specific blood and coagulation products via a 5-point Likert scale. The percentages for each item were calculated for both physicians (n = 110) and rescue service personnel (n = 142) separately as well as an overall score to delineate patterns of agreement or disagreement.

RESULTS

The study reached 9837 individuals, whereby 371 initially answered the questionnaire and 252 participants from Germany were finally included in the statistical analysis. The majority of both physicians (89.1%) and rescue service personnel (90.8%) agreed on the need to improve prehospital trauma care, particularly through the use of blood and coagulation products. Specifically, 60.9% of physicians and 83.8% of rescue personnel supported the prehospital administration of these products. Red blood cell concentrates and fibrinogen were notably endorsed, with 76.2% and 67.1% approval, respectively, for their potential to enhance survival in patients with significant blood loss; however, opinions varied on other blood products.

CONCLUSION

The data demonstrated a readiness to change the trauma approach and confirmed that effective options are available. The utilization of certain products is supported by existing research, underlining the need for their practical implementation in preclinical settings. Here, the emphasis shifts from the isolated time components to the quality of care delivered in an optimized time interval. Ideally, timely and high-quality care should complement each other, leveraging all available therapeutic resources. This could lead to the development of a golden approach to trauma to optimize outcomes in trauma care.

摘要

背景

创伤黄金一小时指的是严重受伤后的关键首个小时,此时及时的医疗反应至关重要,尽管对此时间框架的科学支持并不一致。本研究强调通过根据具体损伤定制治疗方案而非仅关注治疗速度来优化创伤护理。目的是记录改善院前创伤护理的必要性,尤其是通过使用血液及凝血制品。

方法

在一项试点研究之后,一份专门设计的针对德国医生和救援服务人员的在线问卷被用于收集他们对一般创伤护理的看法,特别是关于院前环境中血液及凝血制品的使用。它还通过5分李克特量表评估了九种特定血液及凝血制品的适用性。分别计算了医生(n = 110)和救援服务人员(n = 142)对每个项目的百分比以及总体得分,以描绘同意或不同意的模式。

结果

该研究覆盖了9837人,其中371人最初回答了问卷,最终252名来自德国的参与者被纳入统计分析。大多数医生(89.1%)和救援服务人员(90.8%)都认同有必要改善院前创伤护理,特别是通过使用血液及凝血制品。具体而言,60.9%的医生和83.8%的救援人员支持在院前使用这些制品。红细胞浓缩物和纤维蛋白原尤其得到认可,分别有76.2%和67.1%的人赞成它们对大出血患者提高生存率的潜力;然而,对于其他血液制品,意见存在分歧。

结论

数据表明愿意改变创伤治疗方法,并证实存在有效的选择。现有研究支持某些制品的使用,强调了在临床前环境中实际应用它们的必要性。在此,重点从孤立的时间因素转向在优化的时间间隔内提供的护理质量。理想情况下,及时和高质量的护理应相互补充,利用所有可用的治疗资源。这可能会促成一种创伤黄金治疗方法的发展,以优化创伤护理的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d672/11614957/38cb2b0001ab/101_2024_1482_Fig1_HTML.jpg

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