damsel：在 R 中分析和可视化 DamID 测序结果。
Damsel: analysis and visualisation of DamID sequencing in R.
机构信息
Peter MacCallum Cancer Centre, Melbourne, 3000, Australia.
Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, 3010, Australia.
出版信息
Bioinformatics. 2024 Nov 28;40(12). doi: 10.1093/bioinformatics/btae695.
SUMMARY
DamID sequencing is a technique to map the genome-wide interaction of a protein with DNA. Damsel is the first Bioconductor package to provide an end to end analysis for DamID sequencing data within R. Damsel performs quantification and testing of significant binding sites along with exploratory and visual analysis. Damsel produces results consistent with previous analysis approaches.
AVAILABILITY AND IMPLEMENTATION
The R package Damsel is available for install through the Bioconductor project https://bioconductor.org/packages/release/bioc/html/Damsel.html and the code is available on GitHub https://github.com/Oshlack/Damsel/.
摘要
DamID 测序是一种用于绘制蛋白质与 DNA 全基因组相互作用的技术。Damsel 是第一个在 R 中为 DamID 测序数据提供端到端分析的 Bioconductor 包。Damsel 执行定量和测试显著结合位点，以及探索性和可视化分析。Damsel 产生的结果与以前的分析方法一致。
可用性和实现
R 包 Damsel 可通过 Bioconductor 项目 https://bioconductor.org/packages/release/bioc/html/Damsel.html 进行安装，代码可在 GitHub https://github.com/Oshlack/Damsel/ 上获得。
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