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印度中部严重持续性变应性鼻炎的年龄和性别特异性发病率及变应性鼻炎触发因素的清晰图景。

A Crystal Clear Picture of Age and Gender Specific Incidence of Severe Persistent Allergic Rhinitis and Triggers of Allergic Rhinitis in Central India.

作者信息

Jain Subir

机构信息

Allergologist, ENT Specialist & Surgeon, Indore, M.P India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2024 Dec;76(6):5746-5749. doi: 10.1007/s12070-024-05084-x. Epub 2024 Sep 13.

DOI:10.1007/s12070-024-05084-x
PMID:39559030
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11569326/
Abstract

The prevalence of allergic rhinitis (AR) is associated with various environmental allergens, and the. Level of exposure occurs through inhalation or ingestion. It is clear from several studies and guidelines that screening and identifying various allergens in a particular region can facilitate in diagnosing, treating, and formulating preventive strategies against AR. To study the incidence of severe persistent allergic rhinitis across different age groups and genders, and to identify the allergens responsible for triggering this condition in Central India. The study included 2097 patients of either sex, aged 5 to 70 years suffering from severe persistent allergic rhinitis from January 2003 to Dec 2023. Selection of study group was as per ARIA classification. Modified Skin Prick Test was performed according to the method of Pepys and Bernstein. Study indicates that in Central India, the common allergens responsible for causing severe persistent allergic rhinitis are pre dominantly aero allergens (86%) and food allergens (14%). The three most common aero allergens are house dust mite (D. farinae) (47.97%), housefly (26.23%), and mosquito (25.99%). Among pollens, the most common are Ricinus communis (10.01%), Prosopis juliflora (8.30%), and Gynandropis gynandra (7.15%). Among food allergens, the most common are baker's yeast (2.48%), almond (1.67%), and milk (1.62%). The findings of the study were highly beneficial for counseling on avoidance therapy and making decisions about allergen - specific immunotherapy, which is currently the standard treatment protocol to alter the natural progression of allergic rhinitis.

摘要

过敏性鼻炎(AR)的患病率与多种环境过敏原相关,暴露水平通过吸入或摄入发生。多项研究和指南表明,筛查和识别特定地区的各种过敏原有助于诊断、治疗和制定针对AR的预防策略。为了研究不同年龄组和性别的重度持续性过敏性鼻炎的发病率,并确定印度中部引发这种疾病的过敏原。该研究纳入了2097例年龄在5至70岁之间、患有重度持续性过敏性鼻炎的患者,研究时间为2003年1月至2023年12月。研究组的选择符合ARIA分类标准。改良皮肤点刺试验按照佩皮斯和伯恩斯坦的方法进行。研究表明,在印度中部,导致重度持续性过敏性鼻炎的常见过敏原主要是空气过敏原(86%)和食物过敏原(14%)。三种最常见的空气过敏原是屋尘螨(粉尘螨)(47.97%)、家蝇(26.23%)和蚊子(25.99%)。在花粉中,最常见的是蓖麻(10.01%)、牧豆树(8.30%)和白花菜(7.15%)。在食物过敏原中,最常见的是面包酵母(2.48%)、杏仁(1.67%)和牛奶(1.62%)。该研究结果对于指导避免疗法咨询以及做出关于过敏原特异性免疫疗法的决策非常有益,过敏原特异性免疫疗法目前是改变过敏性鼻炎自然病程的标准治疗方案。

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