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印度班加罗尔过敏性鼻炎患者的变应原敏感性研究。

A study on allergen sensitivity in patients with allergic rhinitis in Bangalore, India.

作者信息

Gowda G, Lakshmi S, Parasuramalu B G, Nagaraj C, Gowda B V C, Somashekara K G

机构信息

Department of Community Medicine,Kempegowda Institute of Medical Sciences, affiliated to the Rajiv Gandhi University of Health Sciences,Bangalore,Karnataka,India.

Department of Otorhinolaryngology,Kempegowda Institute of Medical Sciences, affiliated to the Rajiv Gandhi University of Health Sciences,Bangalore,Karnataka,India.

出版信息

J Laryngol Otol. 2014 Oct;128(10):892-6. doi: 10.1017/S0022215114001984.

DOI:10.1017/S0022215114001984
PMID:25310620
Abstract

BACKGROUND

Allergic rhinitis is the most common form of non-infectious rhinitis, affecting 500 million people worldwide, with one-fifth of those affected living in the Indian subcontinent. The skin prick test is the most valuable test for detecting offending allergens, and can be helpful for patient education, allergen avoidance and immunotherapy planning.

METHOD

The skin prick test was performed with 49 allergens in 486 patients who presented with symptoms of allergic rhinitis, and the allergen profile was studied.

RESULTS

Of the 486 allergic rhinitis patients, 335 (68.93 per cent) showed allergen positivity to the skin prick test. Dust mite was the most common allergen, with positive results in 44.65 per cent of cases.

CONCLUSION

The most common offending allergen in our study was the dust mite. Identification of specific allergens for a particular geographical area aids patient education and enables allergen-specific immunotherapy.

摘要

背景

变应性鼻炎是最常见的非感染性鼻炎形式,全球有5亿人受其影响,其中五分之一的患者生活在印度次大陆。皮肤点刺试验是检测致敏变应原最有价值的试验,有助于患者教育、避免接触变应原和免疫治疗规划。

方法

对486例有变应性鼻炎症状的患者进行了49种变应原的皮肤点刺试验,并研究了变应原谱。

结果

在486例变应性鼻炎患者中,335例(68.93%)皮肤点刺试验显示变应原阳性。尘螨是最常见的变应原,44.65%的病例结果呈阳性。

结论

我们的研究中最常见的致敏变应原是尘螨。确定特定地理区域的特定变应原有助于患者教育,并能实现变应原特异性免疫治疗。

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