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成人型胰腺神经母细胞瘤:一例报告并文献复习

Adult-onset pancreatic neuroblastoma: A case report with a literature review.

作者信息

Alshadood Noufel, Aldarawsha Ali Naser, Al-Badri Sajjad Ghanim, Elazab Mohamed Samy, Mahdi Manar Mohammed, Yousif Flayyih Hasan, Alawad Asdah, Al-Fatlawi Nabeel, Abbas Abbas Hamza, AbdAli Alaa Saeed

机构信息

Warith International Cancer Institute, Karbala, Iraq.

College of Medicine, University of Baghdad, Baghdad, Iraq.

出版信息

Radiol Case Rep. 2024 Nov 6;20(1):539-544. doi: 10.1016/j.radcr.2024.10.066. eCollection 2025 Jan.

Abstract

Neuroblastoma is an aggressive malignancy commonly found in children, with adult patients being quite rare. Pancreatic neuroblastoma, even among adult cases, is especially rare. We present a case of a 26-year-old woman presented with mild abdominal pain and a palpable mass diagnosed as neuroblastoma affecting the pancreas. After initial diagnostic challenges, a biopsy confirmed the diagnosis of neuroblastoma. The patient thereafter underwent a course of neoadjuvant chemotherapy, followed by a complex surgical resection. This case highlights the importance of a comprehensive diagnostic approach, including repeated biopsies and the involvement of a multidisciplinary team in the management of rare presentations of adult neuroblastoma.

摘要

神经母细胞瘤是一种常见于儿童的侵袭性恶性肿瘤,成年患者极为罕见。胰腺神经母细胞瘤,即便在成年病例中,也尤为罕见。我们报告一例26岁女性病例,该患者因轻度腹痛和可触及肿块就诊,诊断为累及胰腺的神经母细胞瘤。经过最初的诊断难题后,活检确诊为神经母细胞瘤。该患者随后接受了新辅助化疗疗程,之后进行了复杂的手术切除。本病例凸显了综合诊断方法的重要性,包括重复活检以及多学科团队参与成人神经母细胞瘤罕见表现的管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/631d/11570904/6029a8a85d86/gr1.jpg

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