Kargl Simon, Frechinger Bettina, Pumberger Wolfgang
Women's and Children's Hospital Linz, Linz, Austria.
Pediatr Surg Int. 2012 Dec;28(12):1239-41. doi: 10.1007/s00383-012-3179-2. Epub 2012 Sep 25.
Neuroblastoma is the most common solid tumor in infancy. Arising from the neural crest these tumors are usually located along the sympathetic chain from the neck to the pelvis and in the adrenal medulla. We report the case of a 3-week-old boy presenting with recurrent episodes of colicky pain. After ultrasound examination, magnetic resonance imaging and laboratory data a pancreatic neuroblastoma was suspected. Tumor resection via distal pancreatectomy and histologic investigation confirmed the diagnosis. Surgery is the treatment of choice in children with pancreatic masses, and is usually well tolerated even in the neonatal period. Conclusive diagnosis can be frequently established only by tumor resection or biopsy. Pancreatic neuroblastoma is an extremely rare tumor with only a few cases described in literature.
神经母细胞瘤是婴儿期最常见的实体瘤。这些肿瘤起源于神经嵴，通常沿交感神经链分布，从颈部至骨盆，以及肾上腺髓质。我们报告一例3周大男婴，表现为反复的绞痛发作。经超声检查、磁共振成像及实验室检查，怀疑为胰腺神经母细胞瘤。通过远端胰腺切除术进行肿瘤切除及组织学检查确诊。对于患有胰腺肿块的儿童，手术是首选治疗方法，即使在新生儿期通常也能耐受良好。往往只有通过肿瘤切除或活检才能做出确切诊断。胰腺神经母细胞瘤是一种极其罕见的肿瘤，文献中仅有少数病例报道。
