Warnock Rachel Koch, Modi Roshan D, Westerman Stacy B
Department of Medicine, Emory University School of Medicine Atlanta, GA.
Division of Cardiology, Emory University School of Medicine Atlanta, GA.
US Cardiol. 2023 Sep 19;17:e12. doi: 10.15420/usc.2022.38. eCollection 2023.
Ventricular arrhythmias, including ventricular tachycardia and VF, commonly occur in patients with underlying cardiomyopathy. Sex differences exist in almost every aspect of ventricular arrhythmia from epidemiology, anatomy, and physiology to management and response to therapy. Some of these may be attributed to variations in etiology, types, and rates of cardiomyopathy as well as biological differences between males and females, but the full explanation for these differences remains incomplete. Additionally, women have been underrepresented in many trials studying therapies for ventricular arrhythmias including ICD placement and ablation; thus, there remains a need for continued research in this population. This review will discuss the differences between the sexes as well as outline opportunities for future research in women with ventricular arrhythmias.
室性心律失常，包括室性心动过速和心室颤动，常见于患有潜在心肌病的患者。从流行病学、解剖学、生理学到管理和治疗反应，室性心律失常的几乎每个方面都存在性别差异。其中一些可能归因于心肌病的病因、类型和发生率的差异以及男性和女性之间的生物学差异，但这些差异的完整解释仍不全面。此外，在许多研究室性心律失常治疗方法（包括植入式心律转复除颤器和消融术）的试验中，女性的代表性不足；因此，仍需要对这一人群继续进行研究。本综述将讨论性别差异，并概述未来对患有室性心律失常的女性进行研究的机会。
