Yamamoto Masayoshi, Yamada Kentaro, Kinoshita Mitsuhiro, Kondo Hiroshi, Oba Hiroshi
Department of Radiology, Teikyo University School of Medicine, Japan.
Interv Radiol (Higashimatsuyama). 2023 Feb 9;9(3):142-148. doi: 10.22575/interventionalradiology.2022-0011. eCollection 2024 Nov 1.
It is more than 50 years since the concept of transjugular intrahepatic portosystemic shunt (TIPS) was first introduced as a percutaneous procedure for patients with refractory variceal bleeding and ascites. TIPS has become widely accepted in the management of complications of portal hypertension because it is less invasive than surgery. In the early days of TIPS, complications included the poor long-term patency of the stent and a high incidence of hepatic encephalopathy. In addition, an excessive shunt diameter after TIPS often resulted in severe hepatic encephalopathy. Although recent covered stents have significantly reduced shunt dysfunction, the development of hepatic encephalopathy and early liver failure remain to be crucial post-TIPS complications. This study reviews the current literature on the status of TIPS in the treatment of cirrhosis.
经颈静脉肝内门体分流术(TIPS)作为一种用于治疗难治性静脉曲张出血和腹水患者的经皮手术首次被提出,至今已有50多年。TIPS已被广泛应用于门静脉高压并发症的治疗,因为它比手术侵入性小。在TIPS开展的早期,并发症包括支架长期通畅性差和肝性脑病发生率高。此外,TIPS术后分流直径过大常导致严重肝性脑病。尽管近年来覆膜支架已显著降低分流功能障碍,但肝性脑病的发生和早期肝功能衰竭仍是TIPS术后的关键并发症。本研究综述了目前关于TIPS治疗肝硬化现状的文献。