Liang Heting, Jiang Zhixia, Yang Xiaoling, Li Shuang, Zhao Xiaoling, Dai Yongya, Liu Siqin, Zhang Yumeng, Yuan Xiaoli
Department of Nursing Affiliated Hospital of Zunyi Medical University Zunyi Guizhou China.
College Office Guizhou Nursing Vocational College Guiyang Guizhou China.
Ibrain. 2023 Aug 9;9(3):281-289. doi: 10.1002/ibra.12124. eCollection 2023 Fall.
To explore the interaction of instrumental activities of daily living (IADLs) and dual sensory function on cognition in the elderly. A cross-sectional survey was conducted in six general hospitals in China, from October 2022 to December 2022. Data collection included general information, IADLs scale, self-reported sensory function questionnaire, and mini-mental state examination (MMSE). Binary logistic regression was used to examine the association between factors and cognition. The interactive effect was evaluated by synergy index (S), relative excess risk due to interaction (RERI), and attributable proportion due to interaction (AP). The odds ratio (OR) of IADLs decline in cognition is 4.412 (95% confidence interval [CI]: 3.633-5.358, < 0.001); the OR of dual sensory difficulty on cognition is 2.502 (95% CI: 1.272-4.921, = 0.008). The OR of interaction between IADLs decline and dual sensory difficulty on cognition is 13.737 (95% CI: 9.726-19.400, < 0.001). RERI (95% CI) = 7.823 (3.230-12.417), AP (95% CI) = 0.570 (0.392-0.747), S (95% CI) = 2.593 (1.616-4.160). IADLs decline and dual sensory difficulty are associated with cognitive decline. IADLs decline and dual sensory difficulty have interaction with cognitive decline; the interaction is greater than the sum effect of those two on cognitive decline independently. Sensory and IADLs assessment can be used as early screening items for cognition among the elderly. In addition, protecting sensory function and maintaining IADLs in the elderly can help protect their cognition.
探讨日常生活工具性活动（IADLs）与双重感觉功能对老年人认知的相互作用。于2022年10月至2022年12月在中国六家综合医院进行了一项横断面调查。数据收集包括一般信息、IADLs量表、自我报告的感觉功能问卷和简易精神状态检查表（MMSE）。采用二元逻辑回归分析因素与认知之间的关联。通过协同指数（S）、交互作用所致相对超额危险度（RERI）和交互作用所致归因比例（AP）评估交互效应。IADLs下降导致认知功能下降的比值比（OR）为4.412（95%置信区间[CI]：3.633 - 5.358，P < 0.001）；双重感觉障碍导致认知功能下降的OR为2.502（95% CI：1.272 - 4.921，P = 0.008）。IADLs下降与双重感觉障碍在认知方面的交互作用的OR为13.737（95% CI：9.726 - 19.400，P < 0.001）。RERI（95% CI） = 7.823（3.230 - 12.417），AP（95% CI） = 0.570（0.392 - 0.747），S（95% CI） = 2.593（1.616 - 4.160）。IADLs下降和双重感觉障碍与认知功能下降相关。IADLs下降和双重感觉障碍与认知功能下降存在交互作用；该交互作用大于两者各自对认知功能下降的单独效应之和。感觉功能和IADLs评估可作为老年人认知的早期筛查项目。此外，保护老年人的感觉功能和维持其IADLs有助于保护其认知功能。
