Marins Tatiana Aporta, de Jesus Graciele Riveres, Holubar Marisa, Salinas Jorge L, Guglielmi Gabrielli Pare, Lin Vivian, de Almeida Silvana Maria
Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.
Stanford University, Stanford, CA, USA.
Antimicrob Steward Healthc Epidemiol. 2024 Nov 11;4(1):e198. doi: 10.1017/ash.2024.342. eCollection 2024.
We performed a systematic literature review to identify and describe pharmacist-led antimicrobial stewardship programs (ASPs) interventions in low- and middle-income countries (LMICs).
Systematic literature review.
We searched PubMed for studies evaluating pharmacist-led ASP interventions in LMICs from January 1, 2012, to November 4, 2023. We evaluated the article's country of origin, described ASP interventions, and analyzed their reported outcomes.
Twenty-four studies were included; ten were conducted in China, two in India, two in Thailand, five in Africa, three in Latin America, and two in the Middle East. The predominant interventions in the studies were education and training followed by audit and feedback. The outcomes reported included reduction in antimicrobial consumption, cost reduction, shortening of the duration of antimicrobial therapy, and de-escalation.
Our findings reinforce the importance of clinical pharmacists leading interventions related to antimicrobial stewardship in LMCIs and the global importance of investing in Infectious Disease training.
我们进行了一项系统的文献综述，以识别和描述在低收入和中等收入国家（LMICs）中由药剂师主导的抗菌药物管理计划（ASPs）干预措施。
系统文献综述。
我们在PubMed上搜索了2012年1月1日至2023年11月4日期间评估在LMICs中由药剂师主导的ASP干预措施的研究。我们评估了文章的原产国，描述了ASP干预措施，并分析了其报告的结果。
纳入了24项研究；其中10项在中国进行，2项在印度进行，2项在泰国进行，5项在非洲进行，3项在拉丁美洲进行，2项在中东进行。研究中的主要干预措施是教育和培训，其次是审核和反馈。报告的结果包括抗菌药物消费减少、成本降低、抗菌治疗持续时间缩短以及降阶梯。
我们的研究结果强化了临床药剂师在LMICs中领导与抗菌药物管理相关干预措施的重要性，以及投资于传染病培训的全球重要性。
