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中国江苏糖尿病防控生物样本库(JBPCD)。

The Jiangsu Biobank for the Prevention and Control of Diabetes (JBPCD) in China.

作者信息

Su Jian, Hang Dong, He Jialiu, Yang Jie, Pan Enchun, Lu Yan, Zhou Zhengyuan, Su Ming, Fang Baoguo, Pan Xiaoqun, Qin Yu, Zhu Zheng, Yu Hao, Han Renqiang, Fan Xikang, Zhou Jinyi, Shen Chong, Wu Ming

机构信息

Jiangsu Provincial Centre for Disease Control and Prevention, Nanjing, China.

Department of Epidemiology, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, School of Public Health, Nanjing Medical University, Nanjing, China.

出版信息

Eur J Epidemiol. 2024 Nov;39(11):1287-1295. doi: 10.1007/s10654-024-01172-y. Epub 2024 Nov 20.

DOI:10.1007/s10654-024-01172-y
PMID:39565534
Abstract

The Jiangsu Biobank for the Prevention and Control of Diabetes (JBPCD) is a community-based prospective cohort study initiated in Jiangsu province, to examine the burden of complications associated with type 2 diabetes mellitus (T2DM). This study aims to better understand the incidence, risk factors, and long-term outcomes of T2DM complications to inform prevention and control strategies. From October 2013 to July 2014, 20,053 T2DM patients (7,862 males and 12,191 females) were recruited from Suzhou city and Huai'an city. Baseline data were collected through questionnaire survey, physical examination and biochemical testing, with blood samples stored in a biobank. The follow-up focused on the incidence and mortality related to T2DM complications, linked to national and local medical datasets. Between August 2019 and October 2020, the repeated assessments were completed for 13,973 participants, including questionnaire, physical examination and repeated blood collection. The study identified 1,479 new cancer cases and 3,324 cardiovascular disease cases, with an overall mortality rate of 25.66 per 1,000 person-years. JBPCD welcomes research collaborations and data access requests via email. Currently, there are no plans to provide cohort data for free public access, but specific proposals for further collaboration are welcome. For further information and collaboration, please email [jswuming@vip.sina.com] and [sc@njmu.edu.cn].

摘要

江苏糖尿病防控生物样本库(JBPCD)是一项始于江苏省的基于社区的前瞻性队列研究,旨在研究2型糖尿病(T2DM)相关并发症的负担。本研究旨在更好地了解T2DM并发症的发病率、危险因素和长期结局,以为预防和控制策略提供依据。2013年10月至2014年7月,从苏州市和淮安市招募了20053例T2DM患者(男性7862例,女性12191例)。通过问卷调查、体格检查和生化检测收集基线数据,并将血液样本存储在生物样本库中。随访重点关注与T2DM并发症相关的发病率和死亡率,并与国家和地方医疗数据集相链接。2019年8月至2020年10月,对13973名参与者完成了重复评估,包括问卷调查、体格检查和重复采血。该研究确定了1479例新癌症病例和3324例心血管疾病病例,总死亡率为每1000人年25.66例。JBPCD欢迎通过电子邮件进行研究合作和数据访问请求。目前,尚无免费向公众提供队列数据的计划,但欢迎提出进一步合作的具体建议。如需进一步信息和合作,请发送电子邮件至[jswuming@vip.sina.com]和[sc@njmu.edu.cn]。

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本文引用的文献

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Increased mortality risk from airborne exposure to polycyclic aromatic hydrocarbons.空气中多环芳烃暴露导致死亡率增加。
J Hazard Mater. 2024 Aug 5;474:134714. doi: 10.1016/j.jhazmat.2024.134714. Epub 2024 May 23.
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Association of lifestyle with reduced stroke risk in 41 314 individuals with diabetes: Two prospective cohort studies in China.生活方式与 41314 名糖尿病患者中风风险降低相关:来自中国的两项前瞻性队列研究。
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Association of gamma-glutamyl transferase concentrations with all-cause and cause-specific mortality in Chinese adults with type 2 diabetes.γ-谷氨酰转移酶浓度与中国 2 型糖尿病患者全因及死因特异性死亡率的关系。
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Microvascular and macrovascular complications of type 2 diabetes mellitus: Exome wide association analyses.2 型糖尿病的微血管和大血管并发症:外显子组全基因组关联分析。
Front Endocrinol (Lausanne). 2023 Mar 23;14:1143067. doi: 10.3389/fendo.2023.1143067. eCollection 2023.
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Diabetes and cancer: Optimising glycaemic control.糖尿病与癌症:优化血糖控制。
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