在稳定选择下维持的加性变异：两个数量性状的多效性双位点模型。
Additive variation maintained under stabilizing selection: a two-locus model of pleiotropy for two quantitative characters.
作者信息
Gimelfarb A
出版信息
Genetics. 1986 Mar;112(3):717-25. doi: 10.1093/genetics/112.3.717.
Abstract
A model with two diallelic loci controlling two additive quantitative characters is suggested. One of the loci has a similar effect on both characters, whereas the second locus has an antagonistic effect on two characters. Both characters experience direct stabilizing selection. The model yields a stable polymorphic state, with both characters maintaining genetic variation. The genetic correlation between the characters at the equilibrium is zero, in spite of the pleiotropic effects of the loci controlling them.
摘要
提出了一个具有两个双等位基因位点控制两个加性数量性状的模型。其中一个位点对两个性状有相似的影响，而第二个位点对两个性状有拮抗作用。两个性状都经历直接的稳定选择。该模型产生一个稳定的多态状态，两个性状都保持遗传变异。尽管控制它们的位点存在多效性效应，但平衡时性状之间的遗传相关性为零。
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