种群大小改变后的纯合性测试。
The homozygosity test after a change in population size.
作者信息
Watterson G A
出版信息
Genetics. 1986 Apr;112(4):899-907. doi: 10.1093/genetics/112.4.899.
Abstract
The homozygosity of a population will be influenced by any recent change in the population size. The "homozygosity test" of the neutral mutation hypothesis might also be influenced by a population change. A computer simulation method is described that establishes the significance levels of observed homozygosities after a change in population size. Some numerical examples are given.
摘要
群体的纯合性会受到群体大小近期任何变化的影响。中性突变假说的“纯合性检验”也可能受到群体变化的影响。本文描述了一种计算机模拟方法，该方法可确定群体大小变化后观察到的纯合性的显著性水平。并给出了一些数值示例。
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