Ngokwe Zilefac Brian, Bienvenue Ntep Ntep David, Stephane Nokam Kamdem, Audrey Kouamou Tchiekou, Charles Bengondo Messanga
Department of Oral Surgery, Maxillofacial Surgery and Periodontology, Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Cameroon; Post Graduate School for Life, Health and Environmental Sciences, University of Yaoundé I, Cameroon.
Department of Oral Surgery, Maxillofacial Surgery and Periodontology, Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Cameroon.
Int J Surg Case Rep. 2024 Dec;125:110628. doi: 10.1016/j.ijscr.2024.110628. Epub 2024 Nov 17.
Albinism, or the loss of pigment formation by otherwise healthy melanocytes, is quite common in Sub-Saharan Africa and is most likely caused by consanguinity. The sun's ultraviolet (UV) radiation and albinism have been both related to non-melanoma skin cancer (NMSC). Non-melanoma skin cancer (NMSC) and melanoma are the two main types of skin cancer. NMSC accounts for the large majority of all skin cancers, they are located in parts of the body that are chronically exposed to sunlight, such as the head, face, neck, and dorsum of the hand.
We present a case of NMSC in a female person with albinism (PWA) presenting with a left facial ulceration and right facial deviation accompanied by intense pain.
The face is home to several vital structures including the facial nerve, which when affected by a tumoral aetiology, albeit uncommon could lead to facial nerve palsy having consequences such as facial appearance changes with potential negative psychosocial effects adding to the weight of the tumour.
Increase awareness of NMSCs and its risk factors, as well early diagnosis and treatment is of the essence and can help reduce morbidity and mortality.
白化病,即原本健康的黑素细胞色素形成缺失,在撒哈拉以南非洲地区颇为常见,很可能是由近亲结婚所致。太阳紫外线辐射与白化病均与非黑素瘤皮肤癌(NMSC)相关。非黑素瘤皮肤癌(NMSC)和黑色素瘤是皮肤癌的两种主要类型。NMSC占所有皮肤癌的绝大多数,它们位于身体长期暴露于阳光的部位,如头部、面部、颈部和手背。
我们报告一例白化病女性患者(PWA)的非黑素瘤皮肤癌病例,该患者表现为左侧面部溃疡和右侧面部偏斜,并伴有剧痛。
面部有多个重要结构,包括面神经,当受到肿瘤病因影响时,尽管不常见,但可能导致面神经麻痹,产生诸如面部外观改变等后果,潜在的负面心理社会影响会加重肿瘤负担。
提高对非黑素瘤皮肤癌及其危险因素的认识,以及早期诊断和治疗至关重要,有助于降低发病率和死亡率。