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采用倾向评分匹配法探讨老年肺结核住院患者的焦虑状况。

Exploring anxiety in elderly pulmonary tuberculosis inpatients using propensity score matching method.

机构信息

Department of Infectious Diseases, Lishui Hospital of Traditional Chinese Medicine Affiliated to Zhejiang University of Traditional Chinese Medicine, Lishui, 323000, China.

出版信息

BMC Pulm Med. 2024 Nov 21;24(1):576. doi: 10.1186/s12890-024-03390-2.

DOI:10.1186/s12890-024-03390-2
PMID:39574047
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11580641/
Abstract

OBJECTIVE

The objective of this study is to explore the factors that influence anxiety in elderly hospitalized pulmonary tuberculosis patients using propensity score matching (PSM) methods.

METHODS

We retrospectively analyzed the clinical data of elderly patients with pulmonary tuberculosis admitted to the tuberculosis Department of Lishui Hospital of Traditional Chinese Medicine from January 2021 to October 2023. The patients were then divided into anxiety and non-anxiety groups based on their GAD-7 scores. Propensity score matching was used to match the baseline data of the two groups, followed by multivariate logistic regression analysis to identify the influencing factors of anxiety in elderly hospitalized pulmonary tuberculosis patients.

RESULTS

The study included 795 elderly hospitalized patients with pulmonary tuberculosis, with 599 classified as carefree and 196 as anxious (32.72%). Using the propensity score matching method, we successfully matched 185 pairs of patients. After matching, there were no statistically significant differences in gender, age, occupation, or other aspects between the two groups of patients (all P > 0.05). Multivariate logistic regression analysis revealed that chronic comorbidities (OR = 2.36, 95% CI: 1.54-3.61), lack of daily social interaction (OR = 1.79, 95% CI: 1.15-2.76), tuberculosis recurrence (OR = 2.08, 95% CI: 1.35-3.21), and lack of daily behavioral ability (OR = 1.99, 95% CI: 1.23-3.23) were influencing factors for anxiety in elderly hospitalized pulmonary tuberculosis patients (P < 0.05).

CONCLUSION

After controlling for confounding factors through PSM, we found that chronic comorbidities, lack of daily social interaction, tuberculosis recurrence, and lack of daily behavioral ability are influencing factors for anxiety in elderly pulmonary tuberculosis inpatients. This suggests a need for clinical intervention.

CLINICAL TRIAL NUMBER

Not applicable.

摘要

目的

本研究旨在采用倾向评分匹配(PSM)方法探讨影响老年住院肺结核患者焦虑的因素。

方法

回顾性分析 2021 年 1 月至 2023 年 10 月丽水市中医院结核科收治的老年肺结核患者的临床资料,根据 GAD-7 评分将患者分为焦虑组和非焦虑组。采用倾向评分匹配法对两组患者的基线资料进行匹配,然后采用多因素 logistic 回归分析识别老年住院肺结核患者焦虑的影响因素。

结果

本研究纳入 795 例老年住院肺结核患者,其中 599 例为无忧组,196 例为焦虑组(32.72%)。采用倾向评分匹配法成功匹配 185 对患者。匹配后,两组患者在性别、年龄、职业等方面差异均无统计学意义(均 P>0.05)。多因素 logistic 回归分析显示,慢性合并症(OR=2.36,95%CI:1.54-3.61)、日常社会交往缺乏(OR=1.79,95%CI:1.15-2.76)、结核病复发(OR=2.08,95%CI:1.35-3.21)、日常行为能力缺乏(OR=1.99,95%CI:1.23-3.23)是老年住院肺结核患者焦虑的影响因素(P<0.05)。

结论

经 PSM 控制混杂因素后,我们发现慢性合并症、日常社会交往缺乏、结核病复发和日常行为能力缺乏是老年肺结核住院患者焦虑的影响因素,这提示需要进行临床干预。

临床试验注册号

无。

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