Kiadaliri Ali, Sirard Paulina, Dahlberg Leif E, Lohmander L Stefan
Department of Clinical Sciences Lund, Orthopaedics, Lund University, Lund, Sweden.
Joint Academy®, Malmö, Sweden.
BMC Sports Sci Med Rehabil. 2024 Nov 21;16(1):232. doi: 10.1186/s13102-024-01020-2.
Physical function constitutes a key component of outcome assessment for almost all osteoarthritis interventions. The aim was to compare physical function measured using a self-assessed performance-based test versus self-reported function using questionnaires among individuals with knee or hip osteoarthritis (OA) participating in a digital exercise and education therapy.
We analysed data from individuals aged 40 + years participating in the digital program. We extracted data on the self-assessed 30-second chair stand test (30s CST) and the function subscales of Knee injury/Hip disability and Osteoarthritis Outcome Score 12 (KOOS-12/HOOS-12) at enrolment and 3- (n = 10884) and 12-month (n = 3554) follow-ups. Participants completed Numeric Rating Scale (NRS) pain, EQ-5D-5L, and an external anchor: global rating of change scale. Correlations were assessed using the Spearman correlation coefficient, responsiveness using standardized response mean (SRM) and receiver operating characteristic (ROC) curves, and agreement using weighted percent of agreement and weighted Gwet's agreement coefficient.
Correlations were weak between the 30s CST and KOOS-12/HOOS-12 function (r < 0.35 for raw and r < 0.20 for change scores). Correlations with NRS pain and EQ-5D-5L were stronger for the KOOS-12/HOOS-12 function subscale than for 30s CST. Greater internal (SRM > 1 vs. SRM < 0.5) and lower external responsiveness were observed for the 30s CST versus the KOOS-12/HOOS-12 function, even though external responsiveness was generally inadequate for both (the area under the ROC curves < 0.7). The direction of change was similar for the two function measures for about 70% of subjects with moderate agreement between them (weighted Gwet's agreement coefficient range 0.45 to 0.50).
Weak correlations and moderate agreements between function measured using performance-based test and self-reported using KOOS-12/HOOS-12 in people with knee or hip OA suggest that they may capture different aspects of functional abilities in this population.
身体功能几乎是所有骨关节炎干预措施结果评估的关键组成部分。目的是比较在参与数字运动和教育治疗的膝或髋骨关节炎（OA）患者中，使用基于自我评估表现的测试测量的身体功能与使用问卷自我报告的功能。
我们分析了参与该数字项目的40岁及以上个体的数据。我们提取了入组时、3个月（n = 10884）和12个月（n = 3554）随访时自我评估的30秒坐立试验（30s CST）以及膝关节损伤/髋关节残疾和骨关节炎结果评分12（KOOS - 12/HOOS - 12）功能子量表的数据。参与者完成了数字评定量表（NRS）疼痛、EQ - 5D - 5L以及一个外部锚定指标：总体变化评定量表。使用Spearman相关系数评估相关性，使用标准化反应均值（SRM）和受试者工作特征（ROC）曲线评估反应性，使用加权一致百分比和加权Gwet一致系数评估一致性。
30s CST与KOOS - 12/HOOS - 12功能之间的相关性较弱（原始数据的r < 0.35，变化分数的r < 0.20）。KOOS - 12/HOOS - 12功能子量表与NRS疼痛和EQ - 5D - 5L的相关性比30s CST更强。与KOOS - 12/HOOS - 12功能相比，30s CST观察到更大的内部反应性（SRM > 1 vs. SRM < 0.5）和更低的外部反应性，尽管两者的外部反应性通常都不足（ROC曲线下面积 < 0.7）。对于约70%的受试者，两种功能测量的变化方向相似，它们之间具有中等一致性（加权Gwet一致系数范围为0.45至0.50）。
在膝或髋OA患者中，基于表现的测试测量的功能与使用KOOS - 12/HOOS - 12自我报告的功能之间存在弱相关性和中等一致性，这表明它们可能反映了该人群功能能力的不同方面。
