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老年骨科共管对患有多种疾病的老年髋部骨折患者的影响:一项非随机对照试验的探索性亚组分析。

Effect of the orthogeriatric co-management on older hip fracture patients with multimorbidity: a post-hoc exploratory subgroup analysis of a non-randomised controlled trial.

机构信息

School of Public Health, Harbin Medical University, 157 Baojian Road,Nangang District, Harbin, 150081, China.

National Centre for Non-Communicable Disease Control and Prevention, Chinese Centre for Disease Control and Prevention, Beijing, China.

出版信息

J Orthop Surg Res. 2024 Nov 21;19(1):780. doi: 10.1186/s13018-024-05263-0.

Abstract

BACKGROUND

Hip fracture and multimorbidity represent significant health challenges for older people. Despite evidence that orthogeriatric co-management improves hip fracture management and patients' health outcomes, there is little evidence to understand its effectiveness for patients with multimorbidity. The study aimed to assess the effect of the orthogeriatric co-management care model on older hip fracture patients with multimorbidity.

METHODS

This study was a post-hoc analysis of a recently completed trial. Patients were admitted to three urban hospitals and three suburban hospitals in Beijing, with diagnosed hip fracture. One urban hospital (intervention group) implemented the orthogeriatric co-management, while other hospitals (control group) continued orthopedics-led usual care. All enrolled patients were followed-up for three times within one year. Study outcome was patients' one-year cumulative adverse events, including re-operation, complication and death. Logistic regression models were used to compare the differences between the intervention and control groups, with adjustment for all potential confounders.

RESULT

A total of 2,071 patients with hip fracture (1,110 intervention, 961 control) were included. More than half of the patients had multimorbidity. Hypertension and diabetes were the leading disease cluster, while hypertension was the most prevalent disease condition across all observed disease clusters. Older hip fracture patients with multimorbidity in the intervention group saw a significantly reduced risk of adverse events compared to the control group (Odds Ratio = 0.59, 95% Confidence Interval: 0.48 to 0.73).

CONCLUSION

Multimorbidity is common among older hip fracture patients. Orthogeriatric co-management provides better outcomes for patients with multimorbidity, in reducing the risk of adverse events after a hip fracture.

CLINICAL TRIAL REGISTRATION INFORMATION

The study was a post-hoc analysis using data from a non-randomized controlled trial. Registry name: Services Mapping Among Older Adults With Hip Fracture (HiFit) ClinicalTrials.gov ID: NCT03184896 URL: https://clinicaltrials.gov/study/NCT03184896.

摘要

背景

髋部骨折和多种合并症对老年人来说是重大的健康挑战。尽管有证据表明骨科-老年科联合管理可改善髋部骨折的管理和患者的健康结局,但对于患有多种合并症的患者,其有效性的证据很少。本研究旨在评估骨科-老年科联合管理护理模式对患有多种合并症的老年髋部骨折患者的效果。

方法

这是一项最近完成的试验的事后分析。患者被收入北京的 3 家城区医院和 3 家郊区医院,均被诊断为髋部骨折。其中 1 家城区医院(干预组)实施骨科-老年科联合管理,而其他医院(对照组)继续采用骨科主导的常规护理。所有入组患者在 1 年内进行了 3 次随访。研究结局为患者的 1 年累积不良事件,包括再次手术、并发症和死亡。采用 logistic 回归模型比较干预组和对照组之间的差异,并对所有潜在混杂因素进行调整。

结果

共纳入 2071 例髋部骨折患者(1110 例干预,961 例对照)。超过一半的患者患有多种合并症。高血压和糖尿病是主要的疾病集群,而高血压是所有观察到的疾病集群中最常见的疾病。与对照组相比,骨科-老年科联合管理组的老年髋部骨折合并症患者不良事件的风险显著降低(优势比=0.59,95%置信区间:0.48 至 0.73)。

结论

多种合并症在老年髋部骨折患者中很常见。骨科-老年科联合管理为患有多种合并症的患者提供了更好的结局,降低了髋部骨折后不良事件的风险。

临床试验注册信息

该研究是一项非随机对照试验的事后分析。研究名称:老年人髋部骨折服务映射(HiFit)。ClinicalTrials.gov 编号:NCT03184896。网址:https://clinicaltrials.gov/study/NCT03184896。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d9d/11580192/3e1effe85b3d/13018_2024_5263_Fig1_HTML.jpg

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