Nagata Yoshika, Yamada Yui, Kinoshita Izumi, Saeki Toshihiro, Fujikawa Takahisa
Surgery, Kokura Memorial Hospital, Kitakyushu, JPN.
Pathology, Kokura Memorial Hospital, Kitakyushu, JPN.
Cureus. 2024 Oct 21;16(10):e72073. doi: 10.7759/cureus.72073. eCollection 2024 Oct.
Breast phyllodes tumors are rare mesenchymal tumors, often accompanied by internal cysts, hemorrhages, infarctions, and necrosis. The tumor exhibits rapid growth, especially when infarct necrosis occurs within the tumor. In the current report, we showed a woman in her 50s who noticed a rapidly growing breast mass and received an excisional biopsy diagnosis of a phyllodes tumor with hemorrhagic infarction. Pathological diagnosis was challenging due to severe hemorrhage and necrosis; however, a comprehensive diagnosis that considered imaging tests recommended appropriate surgical treatment. Here, we report our experience and further analyze the existing literature regarding the prognostic impact of phyllodes tumors enhanced by intratumoral changes.
乳腺叶状肿瘤是罕见的间叶组织肿瘤,常伴有内部囊肿、出血、梗死和坏死。肿瘤生长迅速,尤其是当肿瘤内发生梗死性坏死时。在本报告中,我们展示了一位50多岁的女性,她发现乳房肿块迅速增大,并接受了切除活检,诊断为伴有出血性梗死的叶状肿瘤。由于严重的出血和坏死,病理诊断具有挑战性;然而,综合考虑影像学检查的全面诊断为适当的手术治疗提供了建议。在此,我们报告我们的经验,并进一步分析现有文献中关于肿瘤内变化对叶状肿瘤预后影响的研究。