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医源性膈神经损伤导致双侧膈肌麻痹:一例报告

Bilateral Diaphragmatic Paresis Due to an Iatrogenic Injury of the Phrenic Nerve: A Case Report.

作者信息

Martins Teresa, Hovenkamp Carla, Temido Helena, Martins Joana, Silveira João

机构信息

Physical Medicine and Rehabilitation, Unidade Local de Saúde de Coimbra, Coimbra, PRT.

Internal Medicine, Unidade Local de Saúde de Coimbra, Coimbra, PRT.

出版信息

Cureus. 2024 Oct 22;16(10):e72134. doi: 10.7759/cureus.72134. eCollection 2024 Oct.

Abstract

Bilateral diaphragmatic paresis is a rare entity with unknown incidence and is associated with severe respiratory dysfunction. In this case report we present a 69-year-old patient who sought emergency services due to dyspnea, orthopnea, and paroxysmal nocturnal dyspnea. The patient denied other complaints and mentioned that these symptoms began after being discharged from a hospitalisation for emphysematous acute cholecystitis, where he underwent laparoscopic cholecystectomy, which was complicated by extensive hemorrhage of the abdominal wall. On the physical examination, paradoxical breathing and peripheral oxygen saturation between 80-93% in supine and standing positions, respectively, were notable. The patient was admitted for further investigation, during which thoracic radiographs in inspiration and expiration showed no positional variation of the diaphragm, respiratory function tests revealed a restrictive pattern and electromyography demonstrated acute bilateral diaphragmatic neuropathic injury compatible with phrenic nerve injury. Therefore, by temporal correlation and exclusion of other apparent causes, an etiology in the context of the cholecystectomy was inferred. The patient was evaluated in a multidisciplinary manner and is currently undergoing a cardiopulmonary rehabilitation program in the Physical Medicine and Rehabilitation service, although with limited progress and still requiring non-invasive ventilation.

摘要

双侧膈肌麻痹是一种发病率未知的罕见病症,与严重的呼吸功能障碍有关。在本病例报告中,我们介绍了一名69岁的患者,他因呼吸困难、端坐呼吸和阵发性夜间呼吸困难而寻求急诊服务。患者否认有其他不适,并提到这些症状在因气肿性急性胆囊炎住院出院后开始出现,他在住院期间接受了腹腔镜胆囊切除术,术后出现腹壁广泛出血的并发症。体格检查时,仰卧位和站立位时分别出现矛盾呼吸和外周血氧饱和度在80%-93%之间,这一点值得注意。患者入院接受进一步检查,在此期间,吸气和呼气时的胸部X光片显示膈肌无位置变化,呼吸功能测试显示为限制性模式,肌电图显示急性双侧膈肌神经病变损伤,符合膈神经损伤。因此,通过时间上的相关性和排除其他明显原因,推断病因与胆囊切除术有关。患者接受了多学科评估,目前正在物理医学与康复科接受心肺康复计划,但进展有限,仍需要无创通气。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae2e/11580757/46bebd8e0eb4/cureus-0016-00000072134-i01.jpg

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