Poloni M, Mazzini L, Ceroni M, Tosca P, Bezzi G
Ital J Neurol Sci. 1986 Feb;7(1):63-9. doi: 10.1007/BF02230419.
18 patients with typical sporadic Amyotrophic Lateral Sclerosis (ALS) were investigated by the Motor Accuracy and Speed Test (MAST) and 18 healthy age- and-sex-matched volunteers, acted as controls. All performed each of the five tests 10 times with both the right and the left hands and repeated the experiment after one week by the same procedure. Motor performances were better in the controls than in the ALS patients only in the first three tasks. At retest, one week later, the controls generally improved while ALS patients did not. The mean percentages of changes showed a statistically significant difference in the fifth task. Analysis of the results suggests the possibility that, among the other mechanisms, a disturbance of motor learning ability could be operating in ALS patients.
18例典型散发性肌萎缩侧索硬化症（ALS）患者接受了运动准确性和速度测试（MAST），并选取了18名年龄和性别匹配的健康志愿者作为对照。所有人用右手和左手分别对五项测试各进行10次，并在一周后按照相同程序重复实验。仅在前三项任务中，对照组的运动表现优于ALS患者。一周后的复测中，对照组普遍有所改善，而ALS患者则没有。第五项任务中变化的平均百分比显示出统计学上的显著差异。结果分析表明，在其他机制中，ALS患者可能存在运动学习能力障碍。
