Department of Dentistry, Eastern Mediterranean University (EMU) Famagusta, North Cyprus Mersin 10, Famagusta, Turkey.
Department of Anatomy, Faculty of Medicine, University of Kyrenia, Kyrenia, Northern Cyprus.
Mol Biol Rep. 2024 Nov 22;52(1):10. doi: 10.1007/s11033-024-10106-6.
Infertility is a reproductive health problem in the male or female reproductive system. Traditional assisted reproductive technology (ART) has been unable to solve various cases of infertility for years. Clinical researchers have sought to treat infertility using new methods that are more effective and noninvasive than the old methods. Recently, Mesenchymal stem cells (MSCs) and MSCs-derived Exosomes (MSC-Exos) via paracrine activity play an important role in treating various causes of infertility and improving pregnancy outcomes. In this review, we focus on the roles of MSCs and MSC-Exos cell therapy in female infertility in the different types of female reproductive disorders.
不孕是男性或女性生殖系统的生殖健康问题。传统的辅助生殖技术（ART）多年来一直无法解决各种不孕病例。临床研究人员一直在寻求使用比旧方法更有效和非侵入性的新方法来治疗不孕。最近，间充质干细胞（MSCs）和间充质干细胞衍生的外泌体（MSC-Exos）通过旁分泌活性在治疗各种原因的不孕和改善妊娠结局方面发挥着重要作用。在这篇综述中，我们重点介绍了 MSCs 和 MSC-Exos 细胞疗法在不同类型女性生殖障碍中的女性不孕中的作用。
