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1 型糖尿病产妇分娩期间的血糖控制——现有证据的更新。

Glucose Control During Labour and Delivery in Type 1 Diabetes - An Update on Current Evidence.

机构信息

Center for Pregnant Women with Diabetes, Rigshospitalet, Blegdamsvej 9, Copenhagen, DK-2100, Denmark.

Department of Nephrology and Endocrinology, Rigshospitalet, Blegdamsvej 9, Copenhagen, DK-2100, Denmark.

出版信息

Curr Diab Rep. 2024 Nov 22;25(1):7. doi: 10.1007/s11892-024-01563-1.

DOI:10.1007/s11892-024-01563-1
PMID:39576400
Abstract

PURPOSE OF REVIEW

To provide an update on diabetes management during labour and delivery in women with type 1 diabetes with focus on appropriate insulin administration, carbohydrate supply and use of diabetes technology to support safe delivery and neonatal well-being.

RECENT FINDINGS

During active labour and elective cesarean section capillary blood glucose monitoring or continuous glucose monitoring at least hourly is recommended. Infusion with isotonic (5%) glucose can be given with adjustable infusion rate to address maternal carbohydrate requirements and to prevent maternal hypoglycemia. Subcutaneous insulin administration with multiple injections or insulin pump therapy is considered at least as safe and efficient as intravenous administration to obtain tight glycemic targets. Automated insulin delivery via insulin pump can be continued during labour and delivery. Diabetes management during labour and delivery involves intensive glucose monitoring, adequate insulin administration and carbohydrate administration to support safe delivery and neonatal well-being.

摘要

目的综述

重点介绍 1 型糖尿病女性分娩期间的糖尿病管理,包括适当的胰岛素给药、碳水化合物供应以及使用糖尿病技术以支持安全分娩和新生儿健康。

最新发现

在活跃分娩和选择性剖宫产期间,建议至少每小时监测毛细血管血糖或连续血糖监测。可给予等渗(5%)葡萄糖输注,并可调节输注率以满足产妇的碳水化合物需求并预防产妇低血糖。与静脉内给药相比,多次注射或胰岛素泵治疗的皮下胰岛素给药至少同样安全且有效,以达到严格的血糖目标。通过胰岛素泵的自动胰岛素输送可在分娩和分娩期间继续进行。分娩期间的糖尿病管理包括强化血糖监测、充分的胰岛素给药和碳水化合物给药,以支持安全分娩和新生儿健康。

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Diabetes Technol Ther. 2024 Aug;26(8):596-606. doi: 10.1089/dia.2023.0594. Epub 2024 May 24.
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Automated Insulin Delivery for Pregnant Women With Type 1 Diabetes: Where Do We Stand?自动化胰岛素输注在 1 型糖尿病孕妇中的应用:我们处于什么位置?
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Faster-acting insulin aspart versus insulin aspart in the treatment of type 1 or type 2 diabetes during pregnancy and post-delivery (CopenFast): an open-label, single-centre, randomised controlled trial.
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Off-label use of an automated insulin delivery system in pregnant women with type 1 diabetes.在患有 1 型糖尿病的孕妇中使用自动化胰岛素输送系统的超适应证使用。
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