Fadiloglu Ayse, Cataltepe Esra, Ceker Eda, Allahverdiyeva Seriyye, Samadli Seymur, Sendur Halit Nahit, Güngör Fatih, Varan Hacer Dogan
Department of Internal Medicine, Division of Geriatric Medicine, Faculty of Medicine, Gazi University, 06560, Ankara, Turkey.
Department of Radiology, Faculty of Medicine, Gazi University, Ankara, Turkey.
Eur Geriatr Med. 2025 Feb;16(1):183-190. doi: 10.1007/s41999-024-01103-w. Epub 2024 Nov 22.
The objective of this study is to evaluate the potential of rectus femoris shear wave elastography (RF-SWE) in assessing its impact on frailty and physical performance parameters, using a comparative analysis with rectus femoris muscle thickness (RF-MT).
A total of 149 participants aged 60 and above were included in this research. All participants underwent a comprehensive geriatric assessment, frailty status assessment (using the frailty phenotype [FFP]), and evaluation of physical performance parameters (utilizing the short physical performance battery score [SPPB] and handgrip strength measurement). RF-MT and RF-SWE were measured by a radiologist with participants in a prone and relaxed position.
The mean age of participants was 73.8 ± 6.5, with 61.7% (n = 92) being female. Participants were divided into 2 groups based on their frailty status, with 40 (26.8%) identified as frail and 109 (73.2%) as non-frail. RF-MT exhibited a significant correlation with frailty and the SPPB, while RF-SWE did not exhibit significant associations except for handgrip strength. In regression analyses, RF-MT was found to be significantly and independently associated with physical frailty. The optimal cutoff value for RF-MT was determined to be ≤ 17.74 (area under the ROC curve [AUC], 0.752; 95% CI 0.675-0.819; p < 0.001). In contrast, RF-SWE did not show a significant relationship.
RF-MT is more strongly associated with physical performance and physical frailty than the muscle quality assessed by RF-SWE. Measuring RF-MT, rather than RF-SWE, proves to be an effective tool for predicting frailty in the geriatric population.
本研究的目的是通过与股直肌厚度（RF-MT）进行对比分析，评估股直肌剪切波弹性成像（RF-SWE）在评估其对衰弱和身体性能参数影响方面的潜力。
本研究共纳入149名60岁及以上的参与者。所有参与者均接受了全面的老年评估、衰弱状态评估（使用衰弱表型[FFP]）以及身体性能参数评估（采用简短身体性能量表评分[SPPB]和握力测量）。由放射科医生在参与者俯卧且放松的位置测量RF-MT和RF-SWE。
参与者的平均年龄为73.8±6.5岁，其中61.7%（n = 92）为女性。参与者根据其衰弱状态分为两组，40人（26.8%）被确定为衰弱，109人（73.2%）为非衰弱。RF-MT与衰弱和SPPB显著相关，而RF-SWE除握力外未表现出显著关联。在回归分析中，发现RF-MT与身体衰弱显著且独立相关。RF-MT的最佳截断值确定为≤17.74（ROC曲线下面积[AUC]，0.752；95%CI 0.675 - 0.819；p < 0.001）。相比之下，RF-SWE未显示出显著关系。
与RF-SWE评估的肌肉质量相比，RF-MT与身体性能和身体衰弱的关联更强。测量RF-MT而非RF-SWE被证明是预测老年人群衰弱的有效工具。
