Department of Dental Technology, COAMS, King Khalid University, Abha, 62529, Saudi Arabia.
Department of Dentistry, Oral Health Institute, Hamad Medical Corporation, Doha, Qatar.
BMC Oral Health. 2024 Nov 22;24(1):1426. doi: 10.1186/s12903-024-05013-y.
Resin cement exhibits numerous therapeutic advantages over conventional luting materials. However, the effectiveness of the antibacterial properties of resin cement remains unclear. Nanotechnology provides a viable option, whereby the integration of nanoparticles (NPs) can potentially augment the antibacterial effectiveness of resin cement. The objective of this study was to conduct a comprehensive literature review to assess resin cement's antibacterial effectiveness by incorporating nanoparticles. An extensive search of PubMed and Scopus databases up to September 12, 2023, was conducted to identify relevant scholarly articles that examined and evaluated resin cement's antibacterial effectiveness with and without the incorporation of nanoparticles (NPs). This systematic review adhered to the PRISMA guidelines for reporting the results. The search retrieved seven eligible studies. Studies indicated that resin cement with NPs significantly reduced the colony forming unit (CFU) counts compared to resin cement without NPs. Furthermore, resin cement, in addition to NPs, significantly reduced the bacterial metabolic activity compared to the control group. The use of nanoparticles (NPs) in resin cement has been shown to enhance its antibacterial properties, possibly mitigating the occurrence of secondary caries. Future clinical trials are required to validate the beneficial effects of NPs in conjunction with resin cement in the prevention of secondary caries.
树脂水门汀相对于传统的黏固材料具有许多治疗优势。然而，树脂水门汀的抗菌性能的有效性尚不清楚。纳米技术提供了一种可行的选择，通过将纳米颗粒（NPs）整合，可能会增强树脂水门汀的抗菌效果。本研究的目的是进行全面的文献综述，评估通过加入纳米颗粒来提高树脂水门汀的抗菌效果。截至 2023 年 9 月 12 日，对 PubMed 和 Scopus 数据库进行了广泛的搜索，以确定对树脂水门汀的抗菌效果进行了检查和评估的相关学术文章，包括加入和不加入纳米颗粒（NPs）的情况。本系统评价报告结果符合 PRISMA 指南。搜索共检索到 7 项符合条件的研究。研究表明，与不含 NPs 的树脂水门汀相比，含 NPs 的树脂水门汀显著降低了集落形成单位（CFU）的数量。此外，与对照组相比，树脂水门汀和 NPs 联合使用可显著降低细菌代谢活性。在树脂水门汀中使用纳米颗粒（NPs）已被证明可以增强其抗菌性能，可能有助于减少继发龋的发生。需要进行未来的临床试验来验证 NPs 与树脂水门汀联合使用在预防继发龋方面的有益效果。
