Da Silva Adrielle Firmino, França Saraliny Bezerra, Costa Lucas Fernando De Lima, Dos Santos Ricardo Alexandre, Pinheiro Natália De Araújo, Barros Maria Ester De Sá Barreto, Lima Dimas José Da Paz
Institute of Chemistry and Biotechnology, Federal University of Alagoas, Maceió, Brazil.
Pest Manag Sci. 2025 Mar;81(3):1145-1156. doi: 10.1002/ps.8559. Epub 2024 Nov 23.
The need for implementation of economically viable agrochemicals with lower toxicity and that are capable of overcoming resistance developed by insects, fungi and invasive plants has spurred the scientific community in the search for new active and selective substances and synthetic methodologies that adhere to the parameters of green chemistry. Cinnamamides, in turn, present a scaffold that has been a basis for various investigations due to their broad spectrum of biological activities. The agrochemical industry is a vast field in which these classes of compounds stand out, whether for their potential herbicidal, fungicidal, nematicidal, or insecticidal properties. Therefore, this review reports the progress of synthesis and the agrochemical potential of cinnamamides, their mechanism of action, and their structure-activity relationship (SAR), to provide insights for further research addressing the use of cinnamamides in crop protection. © 2024 Society of Chemical Industry.
需要实施具有较低毒性且能够克服昆虫、真菌和入侵植物产生的抗性的经济可行的农用化学品，这促使科学界寻找符合绿色化学参数的新型活性和选择性物质以及合成方法。肉桂酰胺则提供了一个支架，由于其广泛的生物活性，它一直是各种研究的基础。农用化学工业是一个广阔的领域，这类化合物在其中脱颖而出，无论是因其潜在的除草、杀菌、杀线虫或杀虫特性。因此，本综述报告了肉桂酰胺的合成进展、农用化学潜力、作用机制及其构效关系（SAR），为进一步研究肉桂酰胺在作物保护中的应用提供见解。© 2024化学工业协会。
