Canale S T, Russell T A, Holcomb R L
J Pediatr Orthop. 1986 Mar-Apr;6(2):150-6.
An experimental study was conducted to determine the feasibility of using percutaneous drilling and pneumatic burring under image intensification to effect premature closure of the distal femoral epiphyseal plate in immature New Zealand white rabbits. Serial roentgenograms were made before the animals were killed at 6 or 10 weeks to document leg length inequality as compared with the contralateral leg following the procedure. Microscopic examination of nonoperated and operated epiphyseal plate revealed complete arrest of the operated epiphysis with bone fusion at the epiphyseal plate in eight of the nine rabbits. Since this animal study, 13 children have undergone percutaneous epiphysiodesis. Roentgenographically, all the growth plates appeared fused following the procedure. However, complete growth arrest cannot be substantiated until skeletal maturity. This is a preliminary report of a procedure that needs further documentation.
进行了一项实验研究，以确定在影像增强下使用经皮钻孔和气动磨钻使未成熟新西兰白兔股骨远端骨骺板过早闭合的可行性。在动物于6周或10周处死前拍摄系列X线片，以记录与对侧腿相比术后的腿长不等情况。对未手术和手术的骨骺板进行显微镜检查发现，9只兔子中有8只手术侧骨骺完全停止生长，骨骺板处出现骨融合。自这项动物研究以来，已有13名儿童接受了经皮骨骺阻滞术。X线片显示，术后所有生长板均出现融合。然而，在骨骼成熟之前，无法证实生长完全停止。这是一项需要进一步论证的手术的初步报告。
