Ordoñes-Saucedo Andres, Reyes-Torres Bruno Eduardo, Kortright-Maldonado Karen, Tenorio-Aguirre Erika K, Rodríguez-Henríquez Pedro, Martínez-Sánchez Froylan D
Department of Internal Medicine Hospital General Dr. Manuel Gea Gonzalez Ciudad de México Mexico.
Facultad de Medicina Universidad Nacional Autónoma de México Ciudad de México Mexico.
Clin Case Rep. 2024 Nov 23;12(11):e9621. doi: 10.1002/ccr3.9621. eCollection 2024 Nov.
Acute pancreatitis (AP) is a rare but life-threatening complication in patients with systemic lupus erythematosus (SLE). The case highlights the diagnostic challenges and treatment complexities in managing SLE-associated pancreatitis. A 20-year-old female with a history of SLE presented with acute onset epigastric pain, vomiting, and signs of systemic inflammation. Laboratory findings revealed elevated amylase and lipase levels, confirming AP. Imaging studies showed interstitial edematous pancreatitis and bilateral pleural effusion. The patient was managed with aggressive fluid resuscitation, pain management, and supportive care. A systemic inflammatory response complicated her clinical course, and she required intensive care unit monitoring. This case underscores the importance of early recognition of AP in SLE patients and highlights the need for a multidisciplinary approach to manage this severe complication.
急性胰腺炎（AP）是系统性红斑狼疮（SLE）患者中一种罕见但危及生命的并发症。该病例凸显了管理SLE相关性胰腺炎时的诊断挑战和治疗复杂性。一名有SLE病史的20岁女性出现急性上腹部疼痛、呕吐及全身炎症体征。实验室检查结果显示淀粉酶和脂肪酶水平升高，确诊为AP。影像学研究显示为间质性水肿性胰腺炎和双侧胸腔积液。患者接受了积极的液体复苏、疼痛管理及支持治疗。全身炎症反应使她的临床病程复杂化，她需要重症监护病房监测。该病例强调了早期识别SLE患者中AP的重要性，并凸显了采用多学科方法管理这种严重并发症的必要性。
