Chang Zhijian, Li Shumeng, Ye Jia-Hai, Lin Fuyan, Chen Yuncong, Guo Zijian, Gong Xuedong
School of Chemistry and Chemical Engineering, Nanjing University of Science and Technology, Nanjing, 210094, P. R. China.
State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210093, P. R. China.
Anal Methods. 2024 Dec 19;17(1):178-183. doi: 10.1039/d4ay01922a.
A novel near-infrared fluorescent probe TM2 based on a rhodamine-bearing framework was disclosed with a large Stokes shift (100 nm). TM2 exhibits highly selective recognition for Cu in EtOH/HO (1 : 1, v/v) solution with a low detection limit (2.3 μM) and a wide detection range (0-50 μM). Detection of Cu is undisturbed at physiological pH levels of 5-9. This recognition mechanism is attributed to the formation of a 1 : 1 complex between TM2 and Cu, validated by Job's plot, H NMR titration, and LC-MS experiments. Moreover, the successful fluorescence imaging of Cu both and was also accomplished.
