Shen Guo-Dong, Zhao Zhi-Rong, Bi Kun, Man Yi, Liu Jun-Tong, Huang Xian-Qiang, Lv Xin
School of Chemistry and Chemical Engineering, Liaocheng University, 1 Hunan Avenue, Liaocheng, 252000, Shandong, P. R. China.
College of Chemistry and Life Sciences, Zhejiang Normal University, 688 Yingbin Avenue, Jinhua, 321004, P. R. China.
Mol Divers. 2025 Oct;29(5):4371-4386. doi: 10.1007/s11030-024-11039-9. Epub 2024 Nov 25.
An unprecedented natural light promoted DMSO/O-catalyzed N-acylation reaction of imidazoles/triazoles with cyclopropenones at room temperature under metal-free conditions has been developed. The remarkable advantages of this strategy include atomic economy and environmentally benign conditions (such as natural light promotion, DMSO/O-catalysis, room temperature, and DMC as solvent), stereospecific (E)-olefins synthesis (N-acyl imidazoles and triazoles), wide functional group tolerance and high reaction yields. Furthermore, the typical products (1c and 1e) display good photocurrent and electrochemical property and are potentially applicable in biosensor materials fields.
