Venkataraman P S, Blick K E, Rao R, Fry H D, Parker M K
J Pediatr. 1986 Apr;108(4):607-10. doi: 10.1016/s0022-3476(86)80848-4.
In 10 normal term infants aged 52 +/- 2.5 hours, serum calcium, magnesium, phosphorus, ionized calcium, parathyroid hormone, and calcitonin were studied at 0, 1/2, 1, and 2 hours after administration of 1.77 +/- 0.08 gm/kg glucose orally over 20 minutes. In response to glucose administration, serum glucose concentration rose and serum P, Ca, and Mg concentrations fell. Serum PTH concentration rose significantly, and blood ionized Ca and pH were unaltered. Serum calcitonin was elevated, as compared with adult values, and did not change. We suggest that in neonates, as in adults, oral ingestion of glucose lowers serum Ca, Mg, and P, and a compensatory rise in serum PTH concentration maintains blood ionized Ca concentration.
对10名足月正常婴儿（年龄为52±2.5小时），在20分钟内口服1.77±0.08克/千克葡萄糖后，于0、0.5、1和2小时分别研究其血清钙、镁、磷、离子钙、甲状旁腺激素和降钙素。口服葡萄糖后，血清葡萄糖浓度升高，血清磷、钙和镁浓度下降。血清甲状旁腺激素浓度显著升高，而血离子钙和pH值未改变。与成人值相比，血清降钙素升高，且无变化。我们认为，与成人一样，新生儿口服葡萄糖会降低血清钙、镁和磷，血清甲状旁腺激素浓度的代偿性升高可维持血离子钙浓度。
