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新型根管内药物对根管系统封闭完整性的比较评价：一项体外研究

Comparative Evaluation of Novel Intracanal Medicaments on the Sealing Integrity of the Root Canal System: An In Vitro Study.

作者信息

Barge Prerna, Jadhav Ravindra J, Shaikh Sabina, Kadam Ajay S, Sidral Sandeep Y

机构信息

Pediatric and Preventive Dentistry, Yogita Dental College and Hospital, Khed, IND.

Conservative Dentistry and Endodontics, Vasantdada Patil Dental College and Hospital, Sangli, IND.

出版信息

Cureus. 2024 Oct 26;16(10):e72424. doi: 10.7759/cureus.72424. eCollection 2024 Oct.

DOI:10.7759/cureus.72424
PMID:39588426
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11588327/
Abstract

AIM AND OBJECTIVE

This study aims to evaluate and compare the sealing integrity of endodontically treated teeth after the placement of novel nanoparticle-based intracanal medicaments through dye penetration.

MATERIALS AND METHODS

Total samples (n=56) with different experimental intracanal medicaments group 1: nano calcium oxide (nCaO) + propylene glycol (PPG) 400, group 2: nano zinc oxide (nZnO) + PPG400, group 3: nano magnesium oxide (nMgO) + PPG400, group 4: metapaste (control) were randomly divided for qualitative (n=28) and quantitative (n=28) analysis to determine the sealing integrity. The statistical analysis was performed using ANOVA, student t-test, and IBM SPSS Statistics for Windows, Version 20 (Released 2011; IBM Corp., Armonk, New York, USA), followed by determining sealing integrity using qualitative assay and quantitative assay.

RESULTS

Highly significant differences (p<0.0001) were observed between all four groups during intragroup comparison for qualitative assay. The nCaO-based intracanal medicament showed the maximum linear measurements of 2% methylene blue dye penetrated compared to metapaste. However, intragroup comparison for quantitative assay had non-significant differences (p<0.0001).

CONCLUSION

All intracanal medicaments allowed some leakage to occur. Minimum dye penetration was observed with the metapaste group (control) followed by nano zinc oxide (nZnO) + PPG400, nano magnesium oxide (nMgO) + PPG400, and maximum dye was absorbed with nano calcium oxide (nCaO) + PPG400.

摘要

目的

本研究旨在通过染料渗透评估和比较新型纳米颗粒基根管内药物放置后根管治疗牙齿的封闭完整性。

材料与方法

将总样本（n = 56）分为不同的实验性根管内药物组：第1组为纳米氧化钙（nCaO）+丙二醇（PPG）400，第2组为纳米氧化锌（nZnO）+ PPG400，第3组为纳米氧化镁（nMgO）+ PPG400，第4组为甲硝唑糊剂（对照组），随机分为定性分析（n = 28）和定量分析（n = 28）以确定封闭完整性。使用方差分析、学生t检验以及IBM SPSS Statistics for Windows 20版（2011年发布；IBM公司，美国纽约州阿蒙克）进行统计分析，随后使用定性测定和定量测定确定封闭完整性。

结果

在定性分析的组内比较中，所有四组之间均观察到高度显著差异（p < 0.0001）。与甲硝唑糊剂相比，基于nCaO的根管内药物显示2%亚甲蓝染料渗透的最大线性测量值。然而，定量分析中的组内比较无显著差异（p < 0.0001）。

结论

所有根管内药物均有一定程度的渗漏。甲硝唑糊剂组（对照组）的染料渗透最少，其次是纳米氧化锌（nZnO）+ PPG400、纳米氧化镁（nMgO）+ PPG400，纳米氧化钙（nCaO）+ PPG400吸收的染料最多。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17dc/11588327/b093cb3db013/cureus-0016-00000072424-i09.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17dc/11588327/818ef6b816f7/cureus-0016-00000072424-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17dc/11588327/b5714addb01b/cureus-0016-00000072424-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17dc/11588327/9f2fe0920871/cureus-0016-00000072424-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17dc/11588327/df4b731e5cf7/cureus-0016-00000072424-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17dc/11588327/d6ef749fde72/cureus-0016-00000072424-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17dc/11588327/9c2dac52aff2/cureus-0016-00000072424-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17dc/11588327/efbe3593fed3/cureus-0016-00000072424-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17dc/11588327/3573fcf3b58a/cureus-0016-00000072424-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17dc/11588327/b093cb3db013/cureus-0016-00000072424-i09.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17dc/11588327/818ef6b816f7/cureus-0016-00000072424-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17dc/11588327/b5714addb01b/cureus-0016-00000072424-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17dc/11588327/9f2fe0920871/cureus-0016-00000072424-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17dc/11588327/df4b731e5cf7/cureus-0016-00000072424-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17dc/11588327/d6ef749fde72/cureus-0016-00000072424-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17dc/11588327/9c2dac52aff2/cureus-0016-00000072424-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17dc/11588327/efbe3593fed3/cureus-0016-00000072424-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17dc/11588327/3573fcf3b58a/cureus-0016-00000072424-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17dc/11588327/b093cb3db013/cureus-0016-00000072424-i09.jpg

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