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Alzheimer's disease treatment landscape: current therapies and emerging mechanism-targeted approaches.

作者信息

Yang Eleen, Abd-Elrahman Khaled S

机构信息

Department of Anesthesiology, Pharmacology and Therapeutics, and Djavad Mowafaghian Center for Brain Health, University of British Columbia, Vancouver, BC, Canada (Yang E, Abd-Elrahman KS).

Department of Medical Sciences, College of Medicine and Health Sciences, Khalifa University, Abu Dhabi, United Arab Emirates (Abd-Elrahman KS).

出版信息

Neural Regen Res. 2025 Dec 1;20(12):3531-3532. doi: 10.4103/NRR.NRR-D-24-00934. Epub 2024 Nov 13.

DOI:10.4103/NRR.NRR-D-24-00934
PMID:39589513
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11974664/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8742/11974664/efba010bc3f2/NRR-20-3531-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8742/11974664/efba010bc3f2/NRR-20-3531-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8742/11974664/efba010bc3f2/NRR-20-3531-g001.jpg

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JAMA. 2023 Aug 8;330(6):512-527. doi: 10.1001/jama.2023.13239.
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Amyloid β-based therapy for Alzheimer's disease: challenges, successes and future.阿尔茨海默病的淀粉样β为基础的治疗:挑战、成功与未来。
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Tacrine-Based Hybrids: Past, Present, and Future.他克林类杂合体:过去、现在和未来。
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N Engl J Med. 2023 Jan 5;388(1):9-21. doi: 10.1056/NEJMoa2212948. Epub 2022 Nov 29.
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Alzheimers Dement (N Y). 2022 May 4;8(1):e12295. doi: 10.1002/trc2.12295. eCollection 2022.
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γ-Secretase in Alzheimer's disease.γ-分泌酶在阿尔茨海默病中的作用。
Exp Mol Med. 2022 Apr;54(4):433-446. doi: 10.1038/s12276-022-00754-8. Epub 2022 Apr 8.
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