基于入院时血小板与淋巴细胞比值构建清创术后胫骨骨髓炎复发的列线图：来自中国的一项双中心回顾性研究。

Constructing a nomogram for the recurrence of tibial osteomyelitis after debridement surgery based on platelet to lymphocyte ratio at admission: a dual-center retrospective study from China.

机构信息

Dept. Orthopedics Trauma and Hand Surgery, The First Affiliated Hospital of Guangxi Medical University, NO. 6 ShuangYong Road, Nanning, Guangxi, 530022, China.

Dept. Neurotumor, Beijing Xiaotangshan Hospital, Beijing, 102211, China.

出版信息

BMC Musculoskelet Disord. 2024 Nov 27;25(1):967. doi: 10.1186/s12891-024-08106-5.

AIM

To construction of a nomogram to predict the prognosis of patients with tibial osteomyelitis after debridement surgery.

METHOD

This study used binary logistic regression analysis to identify clinical independent predictive factors, and then used R language to construct a nomogram.

RESULT

The results showed that WBC (3.36[1.77-6.37])、LYM (0.29[0.15-0.54])、BAS (2.19[1.22-3.91])、FIB (0.27[0.14-0.54])、ALB (0.16[0.09-0.3])、TBIL (0.41[0.21-0.83])、D-Dimer (1.77[1.03-3.03])、CRP (0.43[0.2-0.91])、ESR (3.08[1.6-5.79]) and PLR (0.47[0.24-0.9]) were independent predictive factors. Good prediction performance with modest errors was shown by the nomogram in both the training and validation groups.

CONCLUSION

WBC、LYM、BAS、FIB、ALB、TBIL、D-Dimer、CRP、ESR and PLR are independent predictors of the prognosis of patients with tibial osteomyelitis after debridement surgery. The constructed nomogram can help clinicians assess and treat patients early, benefiting more patients.

目的

构建用于预测清创术后胫骨骨髓炎患者预后的列线图。

方法

本研究采用二项逻辑回归分析确定临床独立预测因素，然后使用 R 语言构建列线图。

结果

结果表明，WBC（3.36[1.77-6.37]）、LYM（0.29[0.15-0.54]）、BAS（2.19[1.22-3.91]）、FIB（0.27[0.14-0.54]）、ALB（0.16[0.09-0.3]）、TBIL（0.41[0.21-0.83]）、D-二聚体（1.77[1.03-3.03]）、CRP（0.43[0.2-0.91]）、ESR（3.08[1.6-5.79]）和 PLR（0.47[0.24-0.9]）是独立的预测因素。列线图在训练组和验证组中均表现出适度误差的良好预测性能。