Jelska Alicja, Polecka Agnieszka, Zahorodnii Andrii, Olszewska Ewa
Doctoral School, Medical University of Bialystok, 15-089 Bialystok, Poland.
Department of Otolaryngology, Sleep Apnea Surgery Center, Medical University of Bialystok, 15-089 Bialystok, Poland.
Antioxidants (Basel). 2024 Oct 26;13(11):1300. doi: 10.3390/antiox13111300.
Obstructive sleep apnea (OSA) is a sleep disorder characterized by repeated episodes of apnea and hypopnea, leading to inflammation and oxidative stress that contribute to numerous health complications, including cardiovascular diseases. Continuous positive airway pressure (CPAP) is a standard for treating OSA and is effective in reducing inflammation and oxidative stress. (a black chokeberry), a deciduous shrub belonging to the Rosaceae family and native to eastern North America that is rich in polyphenols, has garnered attention for its therapeutic potential due to its ability to neutralize reactive oxygen species (ROS) and modulate inflammatory pathways, such as NF-κB. This review supports the hypothesis that combining CPAP with black chokeberry supplementation might provide a more comprehensive approach to treating OSA, reducing the risk of health complications by further reducing oxidative stress. In conclusion, has potential benefits as an adjunct therapy in the treatment of OSA, enhancing overall health and well-being. This review compiles the latest scientific findings on the benefits of black chokeberry supplementation, its application in OSA treatment, and its potential use in the treatment of other conditions linked to oxidative stress.
阻塞性睡眠呼吸暂停（OSA）是一种睡眠障碍，其特征为反复出现呼吸暂停和呼吸不足，会导致炎症和氧化应激，进而引发包括心血管疾病在内的多种健康并发症。持续气道正压通气（CPAP）是治疗OSA的标准方法，可有效减轻炎症和氧化应激。黑果腺肋花楸（一种属于蔷薇科的落叶灌木，原产于北美东部，富含多酚）因其具有中和活性氧（ROS）以及调节诸如NF-κB等炎症信号通路的能力，其治疗潜力已受到关注。本综述支持这样一种假设，即CPAP与补充黑果腺肋花楸相结合可能为治疗OSA提供一种更全面的方法，通过进一步减轻氧化应激来降低健康并发症的风险。总之，黑果腺肋花楸作为OSA治疗的辅助疗法具有潜在益处，可增强整体健康和幸福感。本综述汇编了关于补充黑果腺肋花楸的益处、其在OSA治疗中的应用以及其在治疗其他与氧化应激相关病症中的潜在用途的最新科学发现。
