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探索两岁以下儿童的营养状况与腹泻病之间的关系。

Exploring the Relationship of Paediatric Nutritional Status with Diarrhoeal Disease in Children Below Two Years of Age.

作者信息

Khaliq Asif, Nambiar-Mann Smita, Miller Yvette D, Wraith Darren

机构信息

School of Public Health & Social Work, Queensland University of Technology, Brisbane 4059, Australia.

School of Exercise & Nutrition Sciences, Queensland University of Technology, Brisbane 4059, Australia.

出版信息

Children (Basel). 2024 Nov 12;11(11):1374. doi: 10.3390/children11111374.

Abstract

Paediatric malnutrition has a synergistic relationship with diarrhoea. In children under two years of age, diarrhoea occurs in more than half of malnutrition cases and is associated with increased duration of illness, increased length of hospital stays, increased morbidity, and mortality. A well-established relationship exists between diarrhoeal and various standalone forms of malnutrition, but their association with coexisting forms of malnutrition (CFM) has not yet been investigated. Thus, this study assessed the association of CFM with diarrhoea among Pakistani children using datasets retrieved from Demographic Health & Survey and UNICEF. A pooled analysis of datasets of Pakistan Demographic & Health Surveys (PDHS) and Multiple Indicator Cluster Surveys (MICS) from the year 2010 to 2018 was conducted. Data of 70,723 children aged below two years were analysed after excluding those with incomplete anthropometry and outliers. Of the total study population, this study reported the presence of either diarrhoea or malnutrition or both in over half of Pakistani children aged between 0 and 23.9 months. Both standalone forms of undernutrition and coexisting forms of undernutrition were significantly associated with increased odds of diarrhoea by 1.07 (1.02 to 1.12) and 1.21 (1.16 to 1.27) times. The practice of breastfeeding, secondary/higher level of maternal education, and improvement in socioeconomic status reduced the risk of diarrhoea, while the children aged between 6 and 23.9 months residing in urban areas showed a high risk of diarrhoea. The presence of any type of undernutrition, i.e., standalone and/or coexisting forms were associated with increased risk of diarrhoeal diseases in children. An improvement in socioeconomic status, adherence to the continuation of breastfeeding, and maternal education are keys to reducing the burden of diarrhoea among children.

摘要

小儿营养不良与腹泻存在协同关系。在两岁以下儿童中,超过半数的营养不良病例会出现腹泻,且腹泻与疾病持续时间延长、住院时间延长、发病率增加以及死亡率上升相关。腹泻与各种单一形式的营养不良之间存在既定关系,但它们与并存形式的营养不良(CFM)之间的关联尚未得到研究。因此,本研究利用从人口健康与调查以及联合国儿童基金会获取的数据集,评估了巴基斯坦儿童中CFM与腹泻之间的关联。对2010年至2018年巴基斯坦人口与健康调查(PDHS)和多指标类集调查(MICS)的数据集进行了汇总分析。在排除人体测量数据不完整和异常值的儿童后,对70723名两岁以下儿童的数据进行了分析。在整个研究人群中,本研究报告称,在0至23.9个月大的巴基斯坦儿童中,超过半数存在腹泻或营养不良或两者皆有。单一形式的营养不良和并存形式的营养不良均与腹泻几率增加显著相关,分别增加了1.07(1.02至1.12)倍和1.21(1.16至1.27)倍。母乳喂养、母亲接受中等/高等教育以及社会经济地位的改善降低了腹泻风险,而居住在城市地区的6至23.9个月大的儿童腹泻风险较高。任何类型的营养不良,即单一形式和/或并存形式,都与儿童腹泻疾病风险增加相关。社会经济地位的改善、坚持持续母乳喂养以及母亲教育是减轻儿童腹泻负担的关键。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d743/11592731/1fce384c9bdf/children-11-01374-g001.jpg

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