Wilson T M, Therrien A, Harkness J E
Lab Anim Sci. 1986 Feb;36(1):41-4.
Pregnant hamsters were administered diethylstilbestrol (DES) orally on day 14 of gestation. Sperm counts from F1 adult males were lower than controls. Significant and consistent lesions were confined to the epididymides of DES exposed males, in which epididymal granulomas were the most common lesion. Epididymal granulomas of the tail have been associated with a bacterial etiology while granulomas of the head may be related to blind ductules or a lack of ductule connection.
怀孕的仓鼠在妊娠第14天口服己烯雌酚（DES）。F1成年雄性的精子计数低于对照组。显著且一致的病变局限于暴露于DES的雄性的附睾，其中附睾肉芽肿是最常见的病变。尾部的附睾肉芽肿与细菌病因有关，而头部的肉芽肿可能与盲管或缺乏导管连接有关。
