Tubbs Abigail, Vazquez Enrique Alvarez
Biomedical Engineering, College of Engineering and Mines, University of North Dakota, Grand Forks, ND 58202, USA.
Brain Sci. 2024 Oct 30;14(11):1092. doi: 10.3390/brainsci14111092.
In the past five years, repetitive transcranial magnetic stimulation (rTMS) has evolved significantly, driven by advancements in device design, treatment protocols, software integration, and brain-computer interfaces (BCIs). This review evaluates how these innovations enhance the safety, efficacy, and accessibility of rTMS while identifying key challenges such as protocol standardization and ethical considerations. A structured review of peer-reviewed studies from 2019 to 2024 focused on technological and clinical advancements in rTMS, including AI-driven personalized treatments, portable devices, and integrated BCIs. AI algorithms have optimized patient-specific protocols, while portable devices have expanded access. Enhanced coil designs and BCI integration offer more precise and adaptive neuromodulation. However, challenges remain in standardizing protocols, addressing device complexity, and ensuring equitable access. While recent innovations improve rTMS's clinical utility, gaps in long-term efficacy and ethical concerns persist. Future research must prioritize standardization, accessibility, and robust ethical frameworks to ensure rTMS's sustainable impact.
在过去五年中,在设备设计、治疗方案、软件集成和脑机接口(BCI)等方面的进步推动下,重复经颅磁刺激(rTMS)有了显著发展。本综述评估了这些创新如何提高rTMS的安全性、有效性和可及性,同时识别了诸如方案标准化和伦理考量等关键挑战。对2019年至2024年同行评审研究进行的结构化综述聚焦于rTMS的技术和临床进展,包括人工智能驱动的个性化治疗、便携式设备和集成脑机接口。人工智能算法优化了针对特定患者的方案,而便携式设备扩大了可及性。改进的线圈设计和脑机接口集成提供了更精确和自适应的神经调节。然而,在方案标准化、解决设备复杂性以及确保公平可及性方面仍存在挑战。虽然近期的创新提高了rTMS的临床效用,但长期疗效方面的差距和伦理问题依然存在。未来的研究必须优先考虑标准化、可及性和健全的伦理框架,以确保rTMS产生可持续的影响。
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